Phenobarbital and Elsinore Pill
Posted: 05 November 2009 07:40 AM   [ Ignore ]
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Mr. Hobbs,
The original component of Elsinore Pill is ephedrine, caffeine and phenobarbital. What is the purpose of adding phenobarbital, to reduce the side effects of ephedrine or caffeine?

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Posted: 05 November 2009 10:22 AM   [ Ignore ]   [ # 1 ]
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yesure,

The Elsinore Pill was for asthma, so the phenobarbital had something to do with treating asthma.

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Posted: 09 November 2009 08:01 PM   [ Ignore ]   [ # 2 ]
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Mr. Hobbs,

Phenobarbital has no direct pharmacologic effect to treat asthma. It is used as an anticonvulsant clinically. Since barbiturates have affinity for the GABA receptor in the CNS, I reasonably assume that phenobarbital of Elsinore pill might reduce the side effects of ephedrine or caffeine.

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Posted: 09 November 2009 08:24 PM   [ Ignore ]   [ # 3 ]
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yesure,

As you noted originally, I assume the phenobarbital is added to ephedrine and caffeine, or ephedrine and theophylline to counter the stimulating effects.

It has a sedating effect.

If you do a Google search for the “Elsinore Pill” it shows that it contained ephedrine, caffeine and phenobarbital, and was given to asthma patients.

A doctor noticed that these patients were losing weight.

He later gave a modified version of the Elsinore Pill that did not contain the phenobarbital.

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