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Sunday, December 14, 2014

METFORMIN

Is metformin a life-extending drug? Metformin LOWERS risk of death in Type 2 diabetics vs controls

Type 2 diabetics taking metformin were LESS likely to die during a 2.8-year follow-up than non-diabetic controls leading the authors of the study to suggest that metformin might have a life-extending effect even in non-diabetics.

“Patients with type 2 diabetes initiated with metformin monotherapy had longer survival than did matched, non-diabetic controls,” the authors of the paper noted.

“This supports the position of metformin as first-line therapy and implies that metformin may confer benefit in non-diabetes.”

To say this another way, the authors of the study are suggesting that metformin might be life-extending drug in people WITHOUT diabetes.

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Posted by Larry Hobbs on Sun, Dec 14, 2014 12:35 pm | [0] comments

Thursday, October 13, 2011

DIABETES DRUGS

Metformin reduced the risk of death by 36% over 10.7 years in Type 2 diabetics

The diabetes drug metformin (Glucophage) reduced the risk of death by 36% over 10.7 years in Type 2 diabetics according to a 1998 study.


Metformin ALONE was the ONLY diabetes drug to reduce the risk of death.

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Posted by Larry Hobbs on Thu, Oct 13, 2011 3:35 pm | [0] comments

DIABETES DRUGS

Metformin plus a sulphonylurea increased the risk of death 96% over 10.7 years in Type 2 diabetics

Adding the diabetes drug metformin (Glucophage) to Type 2 diabetics who were already taking a sulphonylurea DOUBLED the risk of diabetes-related death -- a 96% increase -- over 10.7 years compared with continued sulphonylurea alone according to a 1998 study.

Metformin alone was the only diabetes drug to reduce the risk of death.

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Posted by Larry Hobbs on Thu, Oct 13, 2011 3:11 pm | [0] comments

Monday, June 23, 2008

AUSTRALIA

Lifestyle intervention reduced the risk for diabetes to a greater extent than metformin (58% vs 31%)

"The Diabetes Prevention Program showed that lifestyle intervention reduced the risk for diabetes to a greater extent than the anti-diabetic drug metformin (58% vs. 31%) (Knowler WC et al, 2002)," according to a report titled Australia's future fat bomb that was written by researchers at the Baker IDI Heart and Diabetes Research Institute in Melbourne, Australia.

The lifestyle-modification program had a goal of losing at least a 7 percent of body weight and at engaging in at least 150 minutes of physical activity per week, while the dose of metformin was 850 mg twice a day.

Note: The report mistakenly stated that metformin only reduced the risk by 13%, but the number should have been 31%. Read the entire article | Email this article
Posted by Larry Hobbs on Mon, Jun 23, 2008 2:56 pm | [0] comments

Thursday, March 15, 2007

METFORMIN

Metformin prevents weight gain from some antipsychotic drugs

Metformin prevented additional weight gain in children who had gained 10 percent or more in less than a year while taking the antipsychotic drugs Zyprexa (olanzapine), Risperdal (risperidone) or Seroquel (quetiapine) according to a study from researchers at Cincinnati Children's Hospital Medical Center in Cincinnati, Ohio, USA. Those given a placebo gained an average of 9 pounds, while those given metformin did not gain an additional weight. Read the entire article | Email this article
Posted by Larry Hobbs on Thu, Mar 15, 2007 2:53 am | [0] comments

Tuesday, September 26, 2006

PROZAC + METFORMIN

Prozac plus metformin caused weight loss of 17.4 lbs

Overweight patients given 20 mg of Prozac (fluoxetine) per day plus 500 mg of the anti-diabetes drug metformin (Glucophage) given three times per day lost an average of 17.4 pounds after six-and-a-half months compared to 1.1 pounds for those not taking the medication according to a new study from Iran. Read the entire article | Email this article
Posted by Larry Hobbs on Tue, Sep 26, 2006 3:18 am | [0] comments

Thursday, May 25, 2006

TOPAMAX & METFORMIN

Topamax plus metformin helped diabetics lose 6.5% of their body weight

Type 2 diabetics taking metformin (Glucophage) and Topamax (topiramate) lost 4.5 to 6.5 percent of their body weight after one year compared to 1.7 percent for those taking only metformin (Glucophage) according to a large study from the Medical University in Graz, Austria. Read the entire article | Email this article
Posted by Larry Hobbs on Thu, May 25, 2006 3:24 am | [0] comments

Tuesday, January 10, 2006

METFORMIN

Metformin causes small amount of weight loss in diabetics, but considerably reduces risk of death

Glucophage (metformin) causes a small amount of weight loss on the order of a couple of pounds when given to patients with diabetes. However, it appears to considerably reduce the risk of diabetes related diseases and death compare to other diabetes treatments according to a new review. Read the entire article | Email this article
Posted by Larry Hobbs on Tue, Jan 10, 2006 12:03 am | [0] comments

Friday, September 09, 2005

PREGNANCY

One-third of infertile obese women become pregnant after taking metformin (Glucophage)

Approximately one-third (6 out of 19, or 32 percent) of obese women with polycystic ovary syndrome (PCOS) who were infertile before treatment, became pregnant within six months of taking the anti-diabetes drug metformin (Glucophage) according to a study from Amman, Jordan. Read the entire article | Email this article
Posted by Larry Hobbs on Fri, Sep 09, 2005 3:26 am | [0] comments

Wednesday, July 06, 2005

DIET VS DRUGS VS SURGERY

Weight loss less than 11 lbs with diet and lifestyle, 11-22 lbs with drugs, and 55-165 lbs w/surgery

When considering only patients who lose at 5 percent of their body weight by the end of weight loss studies, diet and lifestyle changes cause an average weight loss of less than 11 pounds after 2-4 years; weight loss medications cause an average weight loss of 11 to 22 pounds after 1-2 years; and weight loss surgery causes an average weight loss of 55-165 pounds after 2-4 years according to a new review from researchers at McMaster University in Ontario, Canada. Read the entire article | Email this article
Posted by Larry Hobbs on Wed, Jul 06, 2005 7:50 am | [0] comments

Monday, May 16, 2005

POLYCYSTIC OVARY SYNDROME

Increasing the dose of Glucophage (metformin) increases weight loss in women with PCOS

Obese women with polycystic ovary syndrome (PCOS) lost an average of 4.6 pounds more when given a 2250 mg of Glucophage (metformin) compared with 1500 mg per day according to a new study from Glasgow, Scotland. Read the entire article | Email this article
Posted by Larry Hobbs on Mon, May 16, 2005 3:37 pm | [0] comments

Wednesday, March 09, 2005

DIABETES

Xenical (orlistat) reduces the risk of diabetes by 37%, Metformin by 31%, Precose (acarbose) by 25%

Being overweight increases the risk of type 2 diabetes more than any other disease. Xenical (orlistat) reduces the risk of diabetes over a two-to-four year period by 37 percent according to paper from Canada. Read the entire article | Email this article
Posted by Larry Hobbs on Wed, Mar 09, 2005 9:02 am | [0] comments

Monday, February 14, 2005

ACARBOSE / METFORMIN

Acarbose plus diet causes more weight loss in diabetics than metformin plus diet: 7.7 lbs vs 2.2 lbs

Precose (acarbose) caused more weight loss than Glucophage (metformin) in type 2 diabetics according to a recent study. Read the entire article | Email this article
Posted by Larry Hobbs on Mon, Feb 14, 2005 11:07 am | [0] comments

Friday, November 21, 2003

Metformin plus Glyburide causes 20% weight loss in diabetics

SOME STUDIES HAVE SHOWN that type II diabetics lose small amounts of weight using the drug metformin (Glucophage). However combining metformin with glyburide (Micronase) worked significantly better than either one alone according to a recent study. Read the entire article | Email this article
Posted by Larry Hobbs on Fri, Nov 21, 2003 5:50 am | [0] comments
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