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Monday, August 23, 2010

LOW CALORIE DIET

Patients lost 21 pounds or 9.5% of body weight in six weeks on 800 calorie liquid meal replacement

Patients lost an average of 21.2 pounds or 9.5 percent of body weight in six weeks when give a 800 calorie per day liquid meal replacement, which consisted of HMR 800 (Health Management Resources, Boston, Massachusetts, USA).

Information about the HMR 800 meal replacement shakes can be found here.

Note: A couple of weight loss doctors have told me that HMR makes the best meal replacement shakes of any they have tried.

Note: I have no financial ties to HMR or this product. Read the entire article | Email this article
Posted by Admin2 on Mon, Aug 23, 2010 1:56 pm | [0] comments

Wednesday, June 24, 2009

ACOMPLIA

John lost 60 lbs with Taranabant, but found Acomplia had no effect

Here is an interesting post from "JohnTall". I am posting it here so that more people will see it.

"Nearly two years ago I posted a note detailing my experience with Taranabant. In that post I fudged my actual weights for concern that Merck might be able to identify me and end my participation in the trial. Since then Merck has pulled the plug on Taranabant and I am no longer concerned about them knowing that I am posting.

My actual experience was that I started at 244 pounds and I lost to 183 in 101/2 months (61 pounds lost). I then slowly regained 9 pounds to 192 and that was my weight when I left the study in December of 2007. I was in the study for 27 months." Read the entire article | Email this article
Posted by Admin2 on Wed, Jun 24, 2009 11:12 am | [0] comments

Thursday, October 02, 2008

TARANABANT

Merck stops development of the diet drug taranabant because of adverse effects

Merck has dropped development of the diet pill taranabant because of side effects according to a report by the Associated Press.

Comment: The adverse effects must have been pretty serious for them to drop the drug which surely would have made billions of dollars.

I would not be surprised if some subjects given the drug committed suicide as one woman noted that she had constant thoughts of suicide while taking taranabant and warned "In my opinion, this is a very dangerous drug and should not be allowed on the market at all." Read the entire article | Email this article
Posted by Admin2 on Thu, Oct 02, 2008 8:05 am | [3] comments

Tuesday, April 08, 2008

TARANABANT

Taranabant causes women to have fits of rage, crying, disorientation & constant thoughts of suicide

Here is a posting from a woman named Jennifer who was in one of the Taranabant studies who had extreme mood changes and constant thoughts of suicide while on the drug for only three weeks. Read the entire article | Email this article
Posted by Admin2 on Tue, Apr 08, 2008 1:48 pm | [0] comments

Tuesday, April 01, 2008

TARANABANT

Taranabant causes average weight loss of 14.5 lbs in one year vs 5.7 lbs with placebo

A dose of 2 mg of taranabant per day caused an average weight loss of 14.5 lbs in one year when combined with diet compared to 5.7 pounds for those given a placebo according to results presented yesterday at the 57th annual scientific session of the American College of Cardiology. Taranabant is a cannabinoid-1 receptor blocker similar to Acomplia ( rimonabant ). Read the entire article | Email this article
Posted by Admin2 on Tue, Apr 01, 2008 7:28 am | [0] comments

TARANABANT

Taranabant side effects : Gastrointestinal side effects most common

The most commonly reported adverse effect in the taranabant study were gastrointestinal and occurred in 42 percent of those given 2 mg versus 47 percent in 4 mg versus 46 percent in 6 mg and 29 percent given placebo.

Read the entire article | Email this article
Posted by Admin2 on Tue, Apr 01, 2008 7:20 am | [3] comments

TARANABANT

Taranabant side effects : Psychiatric side effects : 28% with 2 mg vs 20% with placebo

Psychiatric side effects were reported more often in those given taranabant than those given a placebo:
  • 28 percent of those given 2 mg

  • 40 percent of those given 4 mg

  • 38 percent of those given 6 mg

  • 20 percent of those given a placebo.
Read the entire article | Email this article
Posted by Admin2 on Tue, Apr 01, 2008 7:15 am | [1] comments

TARANABANT

Taranabant side effects : Crying, tearfulness, and altered mood : 5% with 2 mg vs 3% with placebo

Events related to annxiety and depression, which included crying, tearfulness, altered mood, and mood swings, were reported more often in those given taranabant than those given a placebo:
  • 5 percent of those given 2 mg

  • 7 percent of those given 4 mg

  • 7 percent of those given 6 mg

  • 3 percent of those given a placebo.
Read the entire article | Email this article
Posted by Admin2 on Tue, Apr 01, 2008 7:10 am | [0] comments

TARANABANT

Taranabant side effects : Anxiety : 5% with 2 mg vs 3% with placebo

Anxiety was reported more often in those given taranabant than those given a placebo:
  • 5 percent of those given 2 mg

  • 11 percent of those given 4 mg

  • 9 percent of those given 6 mg

  • 3 percent of those given a placebo.
Read the entire article | Email this article
Posted by Admin2 on Tue, Apr 01, 2008 7:05 am | [0] comments

TARANABANT

Taranabant side effects : Depression : 5% with 2 mg vs 3% with placebo

Depression was reported more often in those given taranabant than those given a placebo:
  • 9 percent of those given 2 mg

  • 11 percent of those given 4 mg

  • 11 percent of those given 6 mg

  • 7 percent of those given a placebo.
Read the entire article | Email this article
Posted by Admin2 on Tue, Apr 01, 2008 7:00 am | [0] comments

TARANABANT

Taranabant side effects : Irritability : 5% with 2 mg vs 2% with placebo

Irritability was reported more often in those given taranabant than those given a placebo:
  • 5 percent of those given 2 mg

  • 9 percent of those given 4 mg

  • 7 percent of those given 6 mg

  • 2 percent of those given a placebo.
Read the entire article | Email this article
Posted by Admin2 on Tue, Apr 01, 2008 6:54 am | [0] comments

TARANABANT

Taranabant side effects : Dropouts to due to side effects : 13% with 2 mg vs 10% with placebo

Those given taranabant were more likely to dropout of the study than those given a placebo:
  • 13 percent of those given 2 mg

  • 10 percent of those given a placebo.
Read the entire article | Email this article
Posted by Admin2 on Tue, Apr 01, 2008 6:49 am | [0] comments

Wednesday, March 12, 2008

TARANABANT

Taranabant : 4 mg reduces food intake by 4% at next meal, 12 mg by 27%

In a one-day, one dose study, 4 mg of taranabant reduced food intake at lunch following the drug by 4 percent, whereas 12 mg reduced food intake by 27 percent compared to people given a placebo. For comparison, 30 of Meridia ( sibutramine ) reduced food intake at lunch by 20 percent. Read the entire article | Email this article
Posted by Admin2 on Wed, Mar 12, 2008 8:04 am | [0] comments

TARANABANT

Taranabant : 4 mg reduces food intake by 1% for one day, 12 mg by 22%

In a one-day, one dose study, 4 mg of taranabant reduced food intake for the day by 1 percent, whereas 12 mg reduced food intake by 22 percent compared to people given a placebo. For comparison, 30 of Meridia ( sibutramine ) reduced food intake by 12 percent. Read the entire article | Email this article
Posted by Admin2 on Wed, Mar 12, 2008 7:53 am | [0] comments

TARANABANT

Taranabant : No specific effect on carb, fat or protein intake

Although taranabant reduced food intake, no particular effect was seen on either carbohydrates, fat or protein. Read the entire article | Email this article
Posted by Admin2 on Wed, Mar 12, 2008 7:34 am | [0] comments

TARANABANT

Taranabant : 12 mg increases metabolism 6% for three hours

In a one-day, one dose study, 12 mg of taranabant increased resting metabolism by 6 percent for three hours compared to 3 percent for when they were given 30 of Meridia ( sibutramine ). Read the entire article | Email this article
Posted by Admin2 on Wed, Mar 12, 2008 7:28 am | [0] comments

Monday, March 10, 2008

TARANABANT

Taranabant : 0.5 mg causes average weight loss of 6.4 lbs in 3 months

A dose of 0.5 mg of the diet drug taranabant causes an average weight loss of 6.4 pounds in three months compared to 2.6 pounds for those given a placebo according to a new paper. Taranabant is similar to Acomplia ( rimonobant ) in that it is a cannabinoid 1 receptor inverse agonist, but it has not been approved for sale. Read the entire article | Email this article
Posted by Admin2 on Mon, Mar 10, 2008 3:09 pm | [0] comments

TARANABANT

Taranabant : 2 mg causes average weight loss of 8.6 lbs in 3 months

A dose of 2 mg of the diet drug taranabant causes an average weight loss of 8.6 pounds in three months compared to 2.6 pounds for those given a placebo according to a new paper. Taranabant is similar to Acomplia ( rimonobant ) in that it is a cannabinoid 1 receptor inverse agonist, but it has not been approved for sale. Read the entire article | Email this article
Posted by Admin2 on Mon, Mar 10, 2008 2:55 pm | [0] comments

TARANABANT

Taranabant : 4 mg causes average weight loss of 9 lbs in 3 months

A dose of 4 mg of the diet drug taranabant causes an average weight loss of 9 pounds in three months compared to 2.6 pounds for those given a placebo according to a new paper. Taranabant is similar to Acomplia ( rimonobant ) in that it is a cannabinoid 1 receptor inverse agonist, but it has not been approved for sale. Read the entire article | Email this article
Posted by Admin2 on Mon, Mar 10, 2008 2:51 pm | [0] comments

TARANABANT

Taranabant : 6 mg causes average weight loss of 11.7 lbs in 3 months

A dose of 6 mg of the diet drug taranabant causes an average weight loss of 11.7 pounds in three months compared to 2.6 pounds for those given a placebo according to a new paper. Taranabant is similar to Acomplia ( rimonobant ) in that it is a cannabinoid 1 receptor inverse agonist, but it has not been approved for sale. Read the entire article | Email this article
Posted by Admin2 on Mon, Mar 10, 2008 2:46 pm | [0] comments

TARANABANT

Taranabant side effects : Anxiety in 3-10% of patients taking 2-6 mg

In a dosing study of the diet drug taranabant, anxiety was reported by
  • 2.9 percent of those given a placebo

  • 1.9 percent of patient given 0.5 mg

  • 2.8 percent of those given 2 mg

  • 4.8 percent of those give 4 mg

  • 10.2 percent of those given 6 mg.
Read the entire article | Email this article
Posted by Admin2 on Mon, Mar 10, 2008 2:40 pm | [0] comments

TARANABANT

Taranabant side effects : Nervousness in 3-4% of patients taking 2-6 mg

In a dosing study of the diet drug taranabant, nervousness was reported by
  • 0.0 percent of those given a placebo

  • 1.9 percent of patient given 0.5 mg

  • 2.8 percent of those given 2 mg

  • 2.9 percent of those give 4 mg

  • 3.7 percent of those given 6 mg.
Read the entire article | Email this article
Posted by Admin2 on Mon, Mar 10, 2008 2:38 pm | [0] comments

TARANABANT

Taranabant side effects : Altered mood in 3-8% of patients taking 2-6 mg

In a dosing study of the diet drug taranabant, inappropriate mood, altered mood, crying or tearfulness was reported by
  • 3.8 percent of those given a placebo

  • 3.8 percent of patient given 0.5 mg

  • 2.8 percent of those given 2 mg

  • 7.6 percent of those give 4 mg

  • 8.3 percent of those given 6 mg.
Read the entire article | Email this article
Posted by Admin2 on Mon, Mar 10, 2008 2:35 pm | [0] comments

TARANABANT

Taranabant side effects : Depression in 6-7% of patients taking 2-6 mg

In a dosing study of the diet drug taranabant, depression was reported by
  • 2.9 percent of those given a placebo

  • 4.7 percent of patient given 0.5 mg

  • 5.5 percent of those given 2 mg

  • 6.7 percent of those give 4 mg

  • 5.6 percent of those given 6 mg.
Read the entire article | Email this article
Posted by Admin2 on Mon, Mar 10, 2008 2:33 pm | [0] comments

TARANABANT

Taranabant side effects : Irritability in 3-9% of patients taking 2-6 mg

In a dosing study of the diet drug taranabant, irritability was reported by
  • 1.9 percent of those given a placebo.

  • 7.5 percent of patient given 0.5 mg

  • 7.3 percent of those given 2 mg

  • 8.6 percent of those give 4 mg

  • 2.8 percent of those given 6 mg.
Read the entire article | Email this article
Posted by Admin2 on Mon, Mar 10, 2008 2:29 pm | [0] comments

TARANABANT

Taranabant side effects : Insomnia in 6-7% of patients taking 2-6 mg

In a dosing study of the diet drug taranabant, insomnia was reported by
  • 4.8 percent of those given a placebo

  • 5.7 percent of patient given 0.5 mg

  • 8.3 percent of those given 2 mg

  • 6.7 percent of those give 4 mg

  • 5.6 percent of those given 6 mg.
Read the entire article | Email this article
Posted by Admin2 on Mon, Mar 10, 2008 2:20 pm | [0] comments

TARANABANT

Taranabant side effects : Nausea in 20-30% of patients taking 2-6 mg

In a dosing study of the diet drug taranabant, nausea was reported by
  • 6.7 percent of those given a placebo

  • 10.4 percent of patient given 0.5 mg

  • 18.3 percent of those given 2 mg

  • 31.4 percent of those give 4 mg

  • 30.6 percent of those given 6 mg.
Read the entire article | Email this article
Posted by Admin2 on Mon, Mar 10, 2008 2:10 pm | [0] comments

TARANABANT

Taranabant side effects : Diarrhea in 7-11% of patients taking 2-6 mg

In a dosing study of the diet drug taranabant, diarrhea was reported by
  • 6.7 percent of those given a placebo.

  • 3.8 percent of patient given 0.5 mg

  • 7.3 percent of those given 2 mg

  • 10.5 percent of those give 4 mg

  • 7.4 percent of those given 6 mg.
Read the entire article | Email this article
Posted by Admin2 on Mon, Mar 10, 2008 2:04 pm | [0] comments

TARANABANT

Taranabant side effects : Loose stools in 11-28% of patients taking 2-6 mg

In a dosing study of the diet drug taranabant, frequent bowel movements or loose stools was reported by
  • 9.5 percent of those given a placebo

  • 12.3 percent of patient given 0.5 mg

  • 11.0 percent of those given 2 mg

  • 27.6 percent of those give 4 mg

  • 17.6 percent of those given 6 mg.
Read the entire article | Email this article
Posted by Admin2 on Mon, Mar 10, 2008 2:00 pm | [0] comments

TARANABANT

Taranabant side effects : Vomiting in 6-14% of patients taking 2-6 mg

In a dosing study of the diet drug taranabant, vomiting was reported by
  • 3.8 percent of those given a placebo

  • 2.8 percent of patient given 0.5 mg

  • 5.5 percent of those given 2 mg

  • 9.5 percent of those give 4 mg

  • 13.9 percent of those given 6 mg.
Read the entire article | Email this article
Posted by Admin2 on Mon, Mar 10, 2008 1:55 pm | [0] comments

Sunday, February 24, 2008

TARANABANT

Woman lost 61 lbs on Taranabant with no side effects

Here is another story of a woman in her 50's who lost 61 pounds in one of the Taranabant trials and seemed to have no side effects. Read the entire article | Email this article
Posted by Admin2 on Sun, Feb 24, 2008 1:41 pm | [2] comments

Friday, January 18, 2008

TARANABANT

Man lost 95 lbs on Taranabant with no additional exercise

Here is a story of a man who was in the Taranabant study and lost 95 pounds while taking the drug without any additional exercise, but only by counting calories. Read the entire article | Email this article
Posted by Admin2 on Fri, Jan 18, 2008 9:02 am | [0] comments

Wednesday, October 10, 2007

Taranabant

‘I lost 60 lbs in 10 months on Taranabant’ notes a second subject of Merck’s Phase III trial

Below is a story from a 54-year-old person who lost 60 pounds in 10 months taking Taranabant, a diet drug being developed by Merck. They posted their story in the Discussion Forum, but I wanted to post it here so that more people might see it. This is the second person from the Merck study who has told his story. The first person's story is posted here.
Read the entire article | Email this article
Posted by Admin2 on Wed, Oct 10, 2007 5:30 am | [0] comments

Wednesday, September 05, 2007

Taranabant

‘I lost 50 lbs on Taranabant’ notes one of the Phase III trial subjects

Below is a story by a man in his mid-50's who lost 50 lbs taking Taranabant, a diet drug being developed by Merck. He posted his story in the Discussion Forum, but I wanted to post it here so that more people might see it. Read the entire article | Email this article
Posted by Admin2 on Wed, Sep 05, 2007 1:05 pm | [5] comments
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