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Monday, August 23, 2010
LOW CALORIE DIET
Patients lost 21 pounds or 9.5% of body weight in six weeks on 800 calorie liquid meal replacement
Patients lost an average of 21.2 pounds or 9.5 percent of body weight in six weeks when give a 800 calorie per day liquid meal replacement, which consisted of HMR 800 (Health Management Resources, Boston, Massachusetts, USA).
Information about the HMR 800 meal replacement shakes can be found here.
Note: A couple of weight loss doctors have told me that HMR makes the best meal replacement shakes of any they have tried.
Note: I have no financial ties to HMR or this product. Read the entire article | Email this article
Information about the HMR 800 meal replacement shakes can be found here.
Note: A couple of weight loss doctors have told me that HMR makes the best meal replacement shakes of any they have tried.
Note: I have no financial ties to HMR or this product. Read the entire article | Email this article
Wednesday, June 24, 2009
ACOMPLIA
John lost 60 lbs with Taranabant, but found Acomplia had no effect
Here is an interesting post from "JohnTall". I am posting it here so that more people will see it.
"Nearly two years ago I posted a note detailing my experience with Taranabant. In that post I fudged my actual weights for concern that Merck might be able to identify me and end my participation in the trial. Since then Merck has pulled the plug on Taranabant and I am no longer concerned about them knowing that I am posting.
My actual experience was that I started at 244 pounds and I lost to 183 in 101/2 months (61 pounds lost). I then slowly regained 9 pounds to 192 and that was my weight when I left the study in December of 2007. I was in the study for 27 months." Read the entire article | Email this article
"Nearly two years ago I posted a note detailing my experience with Taranabant. In that post I fudged my actual weights for concern that Merck might be able to identify me and end my participation in the trial. Since then Merck has pulled the plug on Taranabant and I am no longer concerned about them knowing that I am posting.
My actual experience was that I started at 244 pounds and I lost to 183 in 101/2 months (61 pounds lost). I then slowly regained 9 pounds to 192 and that was my weight when I left the study in December of 2007. I was in the study for 27 months." Read the entire article | Email this article
Thursday, October 02, 2008
TARANABANT
Merck stops development of the diet drug taranabant because of adverse effects
Merck has dropped development of the diet pill taranabant because of side effects according to a report by the Associated Press.
Comment: The adverse effects must have been pretty serious for them to drop the drug which surely would have made billions of dollars.
I would not be surprised if some subjects given the drug committed suicide as one woman noted that she had constant thoughts of suicide while taking taranabant and warned "In my opinion, this is a very dangerous drug and should not be allowed on the market at all." Read the entire article | Email this article
Comment: The adverse effects must have been pretty serious for them to drop the drug which surely would have made billions of dollars.
I would not be surprised if some subjects given the drug committed suicide as one woman noted that she had constant thoughts of suicide while taking taranabant and warned "In my opinion, this is a very dangerous drug and should not be allowed on the market at all." Read the entire article | Email this article
Tuesday, April 08, 2008
TARANABANT
Taranabant causes women to have fits of rage, crying, disorientation & constant thoughts of suicide
Here is a posting from a woman named Jennifer who was in one of the Taranabant studies who had extreme mood changes and constant thoughts of suicide while on the drug for only three weeks.
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Tuesday, April 01, 2008
TARANABANT
Taranabant causes average weight loss of 14.5 lbs in one year vs 5.7 lbs with placebo
A dose of 2 mg of taranabant per day caused an average weight loss of 14.5 lbs in one year when combined with diet compared to 5.7 pounds for those given a placebo according to results presented yesterday at the 57th annual scientific session of the American College of Cardiology. Taranabant is a cannabinoid-1 receptor blocker similar to Acomplia ( rimonabant ).
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TARANABANT
Taranabant side effects : Gastrointestinal side effects most common
The most commonly reported adverse effect in the taranabant study were gastrointestinal and occurred in 42 percent of those given 2 mg versus 47 percent in 4 mg versus 46 percent in 6 mg and 29 percent given placebo.
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TARANABANT
Taranabant side effects : Psychiatric side effects : 28% with 2 mg vs 20% with placebo
Psychiatric side effects were reported more often in those given taranabant than those given a placebo:
- 28 percent of those given 2 mg
- 40 percent of those given 4 mg
- 38 percent of those given 6 mg
- 20 percent of those given a placebo.
TARANABANT
Taranabant side effects : Crying, tearfulness, and altered mood : 5% with 2 mg vs 3% with placebo
Events related to annxiety and depression, which included crying, tearfulness, altered mood, and mood swings, were reported more often in those given taranabant than those given a placebo:
- 5 percent of those given 2 mg
- 7 percent of those given 4 mg
- 7 percent of those given 6 mg
- 3 percent of those given a placebo.
TARANABANT
Taranabant side effects : Anxiety : 5% with 2 mg vs 3% with placebo
Anxiety was reported more often in those given taranabant than those given a placebo:
- 5 percent of those given 2 mg
- 11 percent of those given 4 mg
- 9 percent of those given 6 mg
- 3 percent of those given a placebo.
TARANABANT
Taranabant side effects : Depression : 5% with 2 mg vs 3% with placebo
Depression was reported more often in those given taranabant than those given a placebo:
- 9 percent of those given 2 mg
- 11 percent of those given 4 mg
- 11 percent of those given 6 mg
- 7 percent of those given a placebo.
TARANABANT
Taranabant side effects : Irritability : 5% with 2 mg vs 2% with placebo
Irritability was reported more often in those given taranabant than those given a placebo:
- 5 percent of those given 2 mg
- 9 percent of those given 4 mg
- 7 percent of those given 6 mg
- 2 percent of those given a placebo.
TARANABANT
Taranabant side effects : Dropouts to due to side effects : 13% with 2 mg vs 10% with placebo
Those given taranabant were more likely to dropout of the study than those given a placebo:
- 13 percent of those given 2 mg
- 10 percent of those given a placebo.
Wednesday, March 12, 2008
TARANABANT
Taranabant : 4 mg reduces food intake by 4% at next meal, 12 mg by 27%
In a one-day, one dose study, 4 mg of taranabant reduced food intake at lunch following the drug by 4 percent, whereas 12 mg reduced food intake by 27 percent compared to people given a placebo. For comparison, 30 of Meridia ( sibutramine ) reduced food intake at lunch by 20 percent.
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TARANABANT
Taranabant : 4 mg reduces food intake by 1% for one day, 12 mg by 22%
In a one-day, one dose study, 4 mg of taranabant reduced food intake for the day by 1 percent, whereas 12 mg reduced food intake by 22 percent compared to people given a placebo. For comparison, 30 of Meridia ( sibutramine ) reduced food intake by 12 percent.
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TARANABANT
Taranabant : No specific effect on carb, fat or protein intake
Although taranabant reduced food intake, no particular effect was seen on either carbohydrates, fat or protein.
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TARANABANT
Taranabant : 12 mg increases metabolism 6% for three hours
In a one-day, one dose study, 12 mg of taranabant increased resting metabolism by 6 percent for three hours compared to 3 percent for when they were given 30 of Meridia ( sibutramine ).
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Monday, March 10, 2008
TARANABANT
Taranabant : 0.5 mg causes average weight loss of 6.4 lbs in 3 months
A dose of 0.5 mg of the diet drug taranabant causes an average weight loss of 6.4 pounds in three months compared to 2.6 pounds for those given a placebo according to a new paper. Taranabant is similar to Acomplia ( rimonobant ) in that it is a cannabinoid 1 receptor inverse agonist, but it has not been approved for sale.
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TARANABANT
Taranabant : 2 mg causes average weight loss of 8.6 lbs in 3 months
A dose of 2 mg of the diet drug taranabant causes an average weight loss of 8.6 pounds in three months compared to 2.6 pounds for those given a placebo according to a new paper. Taranabant is similar to Acomplia ( rimonobant ) in that it is a cannabinoid 1 receptor inverse agonist, but it has not been approved for sale.
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TARANABANT
Taranabant : 4 mg causes average weight loss of 9 lbs in 3 months
A dose of 4 mg of the diet drug taranabant causes an average weight loss of 9 pounds in three months compared to 2.6 pounds for those given a placebo according to a new paper. Taranabant is similar to Acomplia ( rimonobant ) in that it is a cannabinoid 1 receptor inverse agonist, but it has not been approved for sale.
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TARANABANT
Taranabant : 6 mg causes average weight loss of 11.7 lbs in 3 months
A dose of 6 mg of the diet drug taranabant causes an average weight loss of 11.7 pounds in three months compared to 2.6 pounds for those given a placebo according to a new paper. Taranabant is similar to Acomplia ( rimonobant ) in that it is a cannabinoid 1 receptor inverse agonist, but it has not been approved for sale.
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TARANABANT
Taranabant side effects : Anxiety in 3-10% of patients taking 2-6 mg
In a dosing study of the diet drug taranabant, anxiety was reported by
- 2.9 percent of those given a placebo
- 1.9 percent of patient given 0.5 mg
- 2.8 percent of those given 2 mg
- 4.8 percent of those give 4 mg
- 10.2 percent of those given 6 mg.
TARANABANT
Taranabant side effects : Nervousness in 3-4% of patients taking 2-6 mg
In a dosing study of the diet drug taranabant, nervousness was reported by
- 0.0 percent of those given a placebo
- 1.9 percent of patient given 0.5 mg
- 2.8 percent of those given 2 mg
- 2.9 percent of those give 4 mg
- 3.7 percent of those given 6 mg.
TARANABANT
Taranabant side effects : Altered mood in 3-8% of patients taking 2-6 mg
In a dosing study of the diet drug taranabant, inappropriate mood, altered mood, crying or tearfulness was reported by
- 3.8 percent of those given a placebo
- 3.8 percent of patient given 0.5 mg
- 2.8 percent of those given 2 mg
- 7.6 percent of those give 4 mg
- 8.3 percent of those given 6 mg.
TARANABANT
Taranabant side effects : Depression in 6-7% of patients taking 2-6 mg
In a dosing study of the diet drug taranabant, depression was reported by
- 2.9 percent of those given a placebo
- 4.7 percent of patient given 0.5 mg
- 5.5 percent of those given 2 mg
- 6.7 percent of those give 4 mg
- 5.6 percent of those given 6 mg.
TARANABANT
Taranabant side effects : Irritability in 3-9% of patients taking 2-6 mg
In a dosing study of the diet drug taranabant, irritability was reported by
- 1.9 percent of those given a placebo.
- 7.5 percent of patient given 0.5 mg
- 7.3 percent of those given 2 mg
- 8.6 percent of those give 4 mg
- 2.8 percent of those given 6 mg.
TARANABANT
Taranabant side effects : Insomnia in 6-7% of patients taking 2-6 mg
In a dosing study of the diet drug taranabant, insomnia was reported by
- 4.8 percent of those given a placebo
- 5.7 percent of patient given 0.5 mg
- 8.3 percent of those given 2 mg
- 6.7 percent of those give 4 mg
- 5.6 percent of those given 6 mg.
TARANABANT
Taranabant side effects : Nausea in 20-30% of patients taking 2-6 mg
In a dosing study of the diet drug taranabant, nausea was reported by
- 6.7 percent of those given a placebo
- 10.4 percent of patient given 0.5 mg
- 18.3 percent of those given 2 mg
- 31.4 percent of those give 4 mg
- 30.6 percent of those given 6 mg.
TARANABANT
Taranabant side effects : Diarrhea in 7-11% of patients taking 2-6 mg
In a dosing study of the diet drug taranabant, diarrhea was reported by
- 6.7 percent of those given a placebo.
- 3.8 percent of patient given 0.5 mg
- 7.3 percent of those given 2 mg
- 10.5 percent of those give 4 mg
- 7.4 percent of those given 6 mg.
TARANABANT
Taranabant side effects : Loose stools in 11-28% of patients taking 2-6 mg
In a dosing study of the diet drug taranabant, frequent bowel movements or loose stools was reported by
- 9.5 percent of those given a placebo
- 12.3 percent of patient given 0.5 mg
- 11.0 percent of those given 2 mg
- 27.6 percent of those give 4 mg
- 17.6 percent of those given 6 mg.
TARANABANT
Taranabant side effects : Vomiting in 6-14% of patients taking 2-6 mg
In a dosing study of the diet drug taranabant, vomiting was reported by
- 3.8 percent of those given a placebo
- 2.8 percent of patient given 0.5 mg
- 5.5 percent of those given 2 mg
- 9.5 percent of those give 4 mg
- 13.9 percent of those given 6 mg.
Sunday, February 24, 2008
TARANABANT
Woman lost 61 lbs on Taranabant with no side effects
Here is another story of a woman in her 50's who lost 61 pounds in one of the Taranabant trials and seemed to have no side effects.
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Friday, January 18, 2008
TARANABANT
Man lost 95 lbs on Taranabant with no additional exercise
Here is a story of a man who was in the Taranabant study and lost 95 pounds while taking the drug without any additional exercise, but only by counting calories.
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Wednesday, October 10, 2007
Taranabant
‘I lost 60 lbs in 10 months on Taranabant’ notes a second subject of Merck’s Phase III trial
Below is a story from a 54-year-old person who lost 60 pounds in 10 months taking Taranabant, a diet drug being developed by Merck. They posted their story in the Discussion Forum, but I wanted to post it here so that more people might see it. This is the second person from the Merck study who has told his story. The first person's story is posted here.
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Wednesday, September 05, 2007
Taranabant
‘I lost 50 lbs on Taranabant’ notes one of the Phase III trial subjects
Below is a story by a man in his mid-50's who lost 50 lbs taking Taranabant, a diet drug being developed by Merck. He posted his story in the Discussion Forum, but I wanted to post it here so that more people might see it.
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