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Friday, October 08, 2010
MERIDIA
Sales of the Diet Drug Meridia (sibutramine) Halted in the U.S.
The diet drug Meridia (sibutramine) will no longer be sold in the U.S. per a request by the U.S. Food and Drug Administration (FDA).
"FDA requested this action after concluding Meridia's continued availability is not justified since patients who take the drug are at an increased risk of heart attacks or strokes," the FDA's Dr. John Jenkins said in media briefing. Read the entire article | Email this article
"FDA requested this action after concluding Meridia's continued availability is not justified since patients who take the drug are at an increased risk of heart attacks or strokes," the FDA's Dr. John Jenkins said in media briefing. Read the entire article | Email this article
Monday, September 13, 2010
MERIDIA
FDA considers pulling Meridia (sibutramine) off the market
The US Food and Drug Administration is considering pulling the diet drug Meridia (sibutramine) off the market because of an increased risk of heart attack and strokes notes a story from the Associated Press.
"Given the modest decrease in body weight associated with sibutramine and the potentially substantial weight regain with discontinuation of therapy, even a small increase in cardiovascular risk seems unwarranted," states Dr. Simone Pinheiro, of the FDA's epidemiology division.
Earlier this month, the editors of the New England Journal of Medicine said that FDA should pull the drug off the market.
European regulators pulled the product off the market in January. Read the entire article | Email this article
"Given the modest decrease in body weight associated with sibutramine and the potentially substantial weight regain with discontinuation of therapy, even a small increase in cardiovascular risk seems unwarranted," states Dr. Simone Pinheiro, of the FDA's epidemiology division.
Earlier this month, the editors of the New England Journal of Medicine said that FDA should pull the drug off the market.
European regulators pulled the product off the market in January. Read the entire article | Email this article
Wednesday, September 01, 2010
SYMLIN (PRAMLINTIDE) + PHENTERMINE
Symlin (pramlintide) + Meridia caused weight loss of 23.9 lbs in six months vs 4.6 lbs w/placebo
Diabetic patients who took Meridia (sibutramine) in addition to giving themselves subcutaneous injections of Symlin (pramlintide), as well as diet, exercise and lifestyle changes, lost an average of 23.9 lbs in six months versus 4.6 lbs in those given injections of a placebo, a difference of 19.3 lbs according to a new study from the makers of Symlin (pramlintide).
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Wednesday, November 25, 2009
MERIDIA
Meridia increases heart attacks, strokes and cardiac arrest in older people says FDA
The diet drug Meridia (sibutramine) increases the risk of heart attack, stroke and cardiac arrest in older people with a history of heart disease or Type 2 diabetes according to information released from the US Food and Drug Administration on November 20th, 2009.
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Tuesday, September 29, 2009
MERIDIA
Meridia (sibutramine) ingestion resulted in no serious effects or deaths in California in 10 years
Among 62 cases of Meridia (sibutramine) overdose reported to the California Poison Control System database between January 1998 and August 1, 2008, there were "no serious effects or deaths on our retrospective case series" notes a new report.
"Mild to moderate effects that were rarely reported included tachycardia [a racing heart], chest pain, agitation, irritation, dizziness, vertigo, nausea, and vomiting."
"The doses ranged from 2.5 to 75 mg."
(The recommended dose is 10-15 mg.) Read the entire article | Email this article
"Mild to moderate effects that were rarely reported included tachycardia [a racing heart], chest pain, agitation, irritation, dizziness, vertigo, nausea, and vomiting."
"The doses ranged from 2.5 to 75 mg."
(The recommended dose is 10-15 mg.) Read the entire article | Email this article
Friday, April 24, 2009
MERIDIA
Meridia (sibutramine) used by 49% of weight loss doctors surveyed
Nearly half (49%) of weight loss doctors surveyed use the diet drug Meridia (sibutramine) with their weight loss patients.
It is the fifth most used diet drug used by these doctors. Read the entire article | Email this article
It is the fifth most used diet drug used by these doctors. Read the entire article | Email this article
Monday, November 10, 2008
MERIDIA
Meridia (sibutramine) plus lifestyle changes caused weight loss of 18 lbs (8.4%) after six months
People given Meridia (sibutramine) plus lifestyle changes lost an average of approximately 18 pounds or 8.4 percent of body weight after six months according to a recent review paper.
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MERIDIA
Meridia (sibutramine) plus lifestyle changes caused weight loss of 18 lbs (8.4%) after six months
People given Meridia (sibutramine) plus lifestyle changes lost an average of approximately 18 pounds or 8.4 percent of body weight after one year according to a recent review paper.
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MERIDIA
Meridia (sibutramine) plus lifestyle changes caused weight loss of 25 lbs (11%) after two years
People given Meridia (sibutramine) plus lifestyle changes lost an average of approximately 25 pounds or 11 percent of body weight after two years according to a recent review paper.
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Friday, September 12, 2008
PRAMLINTIDE
Symlin (pramlintide) (120 mcg three times per day) plus 10 mg Meridia caused weight loss of 24.9 lbs
People injecting 120 mcg of the diabetes drug Symlin (pramlintide) three times per day plus dietary counseling plus 10 mg of Meridia (sibutramine) in the morning lost an average of 24.9 pounds in six months compared to 4.6 pounds for those given a placebo (injections plus pills) according to a study by Amy Halseth, MD from Amylin Pharmaceuticals, San Diego, California presented at the European Association for the Study of Diabetes 2008.
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Tuesday, June 03, 2008
MERIDIA / XENICAL
Meridia (sibutramine) causes an average weight loss of 4.8 lbs greater than Xenical (orlistat)
Meridia (sibutramine) causes an average of 4.8 pounds greater weight loss than Xenical (orlistat) according to a comparison of eight studies involving a total of 885 patients that compared the two drugs. The studies lasted from 3 to 12 months.
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Tuesday, December 18, 2007
XENICAL
1.6% of Meridia users stop taking the drug within 3 months due to hypertension
The most common reason for stopping Meridia (sibutramine) within the first three months was hypertension, causing 1.6 percent of patients to stop taking the drug according to data from the UK.
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MERIDIA
1.6% of Meridia users stop taking the drug within 3 months due to hypertension
The most common reason for stopping Meridia (sibutramine) within the first three months was hypertension, causing 1.6 percent of patients to stop taking the drug according to data from the UK.
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MERIDIA & XENICAL
80% of people taking Meridia and Xenical are women according to British data
Approximately 80 percent of people taking Meridia (sibutramine) and Xenical (orlistat) are women according to prescription data from the UK.
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Friday, November 16, 2007
MERIDIA
Meridia (sibutramine) causes an average weight loss of 9.2 lbs more than placebo
Meridia (sibutramine) causes an average weight loss of 9.2 pounds more than placebo or 4.3 percent of body weight more than placebo according to an analysis by researchers from the University of Alberta in Edmonton, Alberta, Canada.
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Wednesday, October 03, 2007
LONG-TERM MERIDIA & XENICAL USE
Less than 10% of people take Xenical or Meridia for a year; less than 2% take them for 2 years
Less than 10 percent of patients prescribed either Xenical (orlistat) or Meridia (sibutramine) are still taking them after one year, and less than 2 percent are still taking them after two years according to a study from the University of Alberta Hospital in Edmonton, Alberta, Canada.
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Wednesday, June 20, 2007
MERIDIA
Meridia plus meal replacement shakes causes weight loss of 23.8 lbs in one year
Meridia (sibutramine) plus two Slim-Fast meal replacement shakes per day caused an average weight loss of 18.3 pounds after three months and 23.8 pounds after one year according to a study from researchers at the University of Kansas School of Medicine in Wichita, Kansas, USA.
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Wednesday, June 06, 2007
MERIDIA AND TOPAMAX
Overweight bipolar patients lose 8.9 lbs with Meridia, 6.2 lbs with Topamax
Overweight bipolar patients who had gained weight while taking antipsychotic medicine lost an average of 8.9 pounds in six months with Meridia (sibutramine) compared to 6.2 pounds with Topamax (topiramate), however, more than three-fourths of patients dropped out before the end of the study.
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Monday, March 19, 2007
MERIDIA
People lose 9.4 lbs more with 10 mg of Meridia
People given 10 mg of Meridia (sibutramine) per day in addition to a reduced calorie diet lost an average of 18 pounds in six months compared to 8.6 pounds for those given a placebo according to a study from Italy.
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Friday, November 10, 2006
XENICAL / MERIDIA
Xenical (orlistat) plus Meridia (sibutramine) causes weight loss of 14.9%
Men and women given a combination of Xenical (orlistat) plus Meridia (sibutramine) lost 8 percent in three months and 14.9 percent after six months according to a study from Brazil.
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Monday, April 03, 2006
MERIDIA (SIBUTRAMINE)
Meridia (sibutramine) can cause bruising
Meridia (sibutramine) can cause bruising according to 16 cases reported according to a paper from New Zeland.
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Thursday, March 30, 2006
MERIDIA (SIBUTRAMINE)
Meridia (sibutramine) can cause amnesia in rare cases
In rare cases, Meridia (sibutramine) can cause mental impairment according to a report from New Zeland.
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Sunday, March 05, 2006
METABOLISM
Boosting metabolism: Meridia (sibutramine) raises metabolism in men
Meridia (sibutramine), and I assume other noradrenaline reuptake inhibitors, may increase metabolism slightly. They may increase metabolism in men more than women according to the research.
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Wednesday, July 06, 2005
DIET VS DRUGS VS SURGERY
Weight loss less than 11 lbs with diet and lifestyle, 11-22 lbs with drugs, and 55-165 lbs w/surgery
When considering only patients who lose at 5 percent of their body weight by the end of weight loss studies, diet and lifestyle changes cause an average weight loss of less than 11 pounds after 2-4 years; weight loss medications cause an average weight loss of 11 to 22 pounds after 1-2 years; and weight loss surgery causes an average weight loss of 55-165 pounds after 2-4 years according to a new review from researchers at McMaster University in Ontario, Canada.
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Monday, April 25, 2005
MERIDIA
Meridia (sibutramine) causes average weight loss of 9.8 lbs after one year
Meridia (sibutramine) causes an average weight loss of 9.8 pounds more than placebo after one year according to a analysis by the RAND Corporation.
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Tuesday, March 22, 2005
MERIDIA
Meridia (sibutramine) associated with a case of reversible heart failure
A 35-year-old obese man from Turkey developed heart failure after taking the diet drug Meridia (sibutramine) for several months, which reversed after stopping the drug. This may or may not have been cause by the drug, but doctors should be aware of this.
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Friday, December 17, 2004
U.S. NIH’s Obesity Guidelines Part 30: Diet drugs for weight loss
Meridia (sibutramine) and and Xenical (orlistat) are the only diet drugs currently approved for long-term use according to the U.S. NIH's Obesity Guidelines (p. xvi).
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Sunday, December 05, 2004
Meridia (sibutramine): Taking it with food increases absorption 5-fold
Taking the prescription diet pill Meridia (sibutramine) with food dramatically affects absorption according to a new study out of Canada.
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Saturday, December 04, 2004
Meridia (sibutramine): 35 cases of amnesia reported world-wide
Thirty-five cases of amnesia have been reported world-wide associated with the use of the prescription diet pill Meridia (sibutramine) according to a report in the December 4, 2004 issue of the British Medical Journal.
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Friday, October 01, 2004
Meridia causes 9.5 lbs more weight loss than placebo
Meridia (sibutramine) causes an an average weight loss of 9.5 pounds or 5 percent of bodyweight more than placebo according to a recent review paper.
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Tuesday, September 21, 2004
Meridia vs ephedrine: A single dose of Meridia increases resting metabolism, ephedrine does not
A single 10 mg dose of Meridia (sibutramine) increases resting metabolism, whereas a single dose of ephedrine sulphate does not according to a study from researchers at the University of North Carolina's School of Pharmacy.
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Tuesday, September 14, 2004
Meridia causes a weight loss of 15 lbs weight loss in HMO weight loss program
Meridia (sibutramine) caused an average weight loss of 15 pounds after six months in an health maintenance organization (HMO) weight loss program compared to 6.8 pounds for people not taking the drug.
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Prozac, Meridia and Xenical cause weight loss in type 2 diabetics
Prozac (fluoxetine), Meridia (sibutramine) and Xenical (orlistat) have been found to cause weight loss in type 2 diabetics for up to a year.
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Xenical increases weight loss by 7.2 lbs over diet alone; Meridia by 9.2 lbs
Adding the fat-blocking drug Xenical (orlistat) to diet increases weight loss by an average of 7.2 pounds more than diet alone for up to two years according to a new paper which reviewed previous studies.
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Thursday, September 09, 2004
Diet drugs: Phentermine prescribed twice as often as Xenical and three times as often as Meridia
In 2002, phentermine was used to treat obesity twice as often as Xenical (orlistat) and three times as often as Meridia (sibutramine).
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Monday, July 26, 2004
Meridia helps people with Binge Eating Disorder lose 16 lbs in three months
People with binge eating disorder given Meridia (sibutramine) lost 16.3 pounds in three months compared to a weight gain of 3.1 pounds for those given a placebo according to a study from Brazil.
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Thursday, July 22, 2004
Meridia causes 9.5 pounds greater weight loss than placebo
Meridia (sibutramine) causes 9.5 pounds or 4.6 percent more weight loss than placebo according to a reveiw of previous studies.
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Tuesday, July 06, 2004
Xenical plus Meridia plus Topamax causes women to lose 66-77 lbs
Two women who were highly motivated to lose weight lost an average of 72 pounds using a combination of Xenical (orlistat), Meridia (sibutramine), and Topamax (topiramate) according to a paper from Free University in Berlin, Germany.
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Xenical plus Meridia plus Topamax causes men to lose 53-77 lbs
Three men who were highly motivated to lose weight lost an average of 67 pounds using a combination of Xenical (orlistat), Meridia (sibutramine), and Topamax (topiramate) according to a paper from Free University in Berlin, Germany.
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Thursday, June 03, 2004
Diet drugs cause weight losses of 8-17 pounds more than placebo after 9-12 months
Diet drug studies lasting 9 to 12 months show weight losses of 8-17 pounds more than placebo, or 3 to 8 percent of bodyweight, according to a recent review by G. Glazer from the University of Rochester School of Medicine, in New York.
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