Prolonged use of statins for more than 4 years was associated with a 29% increased risk of bladder cancer according to a recent analysis of data from 574 UK general practices from 1998-2008.

High levels of leisure-time physical activity were associated with a lower risk of 13 types of cancer when compared to people with low levels of leisure-time physical activity according to a study done by researchers at the U.S. National Cancer Institute.

The 13 cancers associated with a lower risk were:

• 10% lower risk of breast cancer
• 13% lower risk of bladder cancer
• 13% lower risk of rectal cancer
• 15% lower risk of head and neck cancer
• 16% lower risk of colon cancer
• 17% lower risk of multiple myeloma
• 20% lower risk of myeloid leukemia
• 21% lower risk of endometrial cancer
• 22% lower risk of gastric cardia
• 23% lower risk of kidney cancer
• 26% lower risk of lung cancer
• 27% lower risk of liver cancer
• 42% lower risk of esophageal cancer

Long-term statin use (more than 4 years) is associated with a 29% increased risk of bladder cancer according to a recent review paper titled The Ugly Side of Statins.