People over the age of 65 taking a tricyclic antidepressant were 1.7 times more likely to attempt suicide or self harm during the study period compared to when antidepressants were not being used according to a 2011 study from the U.K.

People over the age of 65 taking a serotonin reuptake inhibitor (SSRI) were 2.2 times more likely to attempt suicide or self harm during the study period compared to when antidepressants were not being used according to a 2011 study from the U.K.