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Monday, May 14, 2018

HEAVY METAL LEAD

Elevated bone lead levels associated with 42% greater risk of cardiovascular death

The one-third of males with the highest lead levels as measured in the kneecap (bone lead levels as opposed to blood lead levels) compared to the one-third with the lowest lead levels were 42% more likely to die from cardiovascular death during an average follow-up of 8.9 years according to the Veterans Affairs Normative Aging Study.

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Posted by Admin2 on Mon, May 14, 2018 1:04 pm | [0] comments

HEAVY METAL LEAD

Elevated bone lead levels associated with 87% greater risk of death from heart disease

The one-third of males with the highest lead levels as measured in the kneecap (bone lead levels as opposed to blood lead levels) compared to the one-third with the lowest lead levels were 87% more likely to die from ischemic heart disease (reduced blood supply to the heart) during an average follow-up of 8.9 years according to the Veterans Affairs Normative Aging Study.

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Posted by Admin2 on Mon, May 14, 2018 12:47 pm | [0] comments

Tuesday, October 18, 2016

RESTING METABOLISM

Resting metabolism falls by 25 calories per day for every 2.2 lbs lost from liposuction

Resting metabolism slows by 25 calories per day for every 2.2 pounds that is lost from weight loss due to liposuction surgery according to a 2009 paper by Eric Doucet and A. Schwartz from the University of Ottawa in Ottawa, Ontario, Canada.

This may be because body fat releases leptin, a hormone which decreases appetite and increases metabolism, therefore, by removing fat cells, liposuction may decrease leptin levels, and thus, decrease resting metabolism.

Studies have shown that giving leptin injections "reverse the effects of weight loss on resting [metabolism]," the paper notes.

This was much greater than the decrease of 15 calories per day seen with weight loss from a low-calorie diet, and the 11 calorie decrease seen with weight loss surgery. Read the entire article | Email this article
Posted by Admin2 on Tue, Oct 18, 2016 9:15 am | [0] comments

Saturday, October 15, 2011

FRUCTOSE

Fructose causes obesity by causing leptin resistance says Robert Lustig, MD

Fructose causes obesity by raising insulin, causing insulin resistance which causes leptin resistance which reduces metabolism and increases appetite says Robert Lustig, MD.

"Our environment is insulinogenic. We have to get the insulin down," Lustig notes in a slide show. Read the entire article | Email this article
Posted by Admin2 on Sat, Oct 15, 2011 12:02 pm | [0] comments

Wednesday, November 03, 2010

SLEEP

Short sleep reduces the appetite-suppressing hormone leptin, increases appetite-stimulating ghrelin

Shortened sleep reduces leptin, a hormone which reduces appetite, and increases ghrelin, a hormone which increases appetite notes a review paper on the association of lack of sleep to obesity and diabetes.
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Posted by Admin2 on Wed, Nov 03, 2010 5:52 am | [0] comments

Tuesday, October 12, 2010

FRUCTOSE

Fructose may increase appetite by lowering leptin and increasing ghrelin

A dramatic increase in the consumption of hIgh-fructose corn syrup in recent years may help explain the recent obesity epidemic as explained in previous articles. One of the reasons may be that fructose does not stimulate the release of insulin the way that glucose does and thus does not stimulate the release of leptin according to a paper from researchers at the University of California, Davis. Read the entire article | Email this article
Posted by Admin2 on Tue, Oct 12, 2010 6:27 am | [0] comments

Thursday, October 16, 2008

FRUCTOSE

Fructose causes leptin resistance and more weight gain when fed a high-fat diet

Feeding rats a diet containing 60 percent fructose for six months caused leptin resistance and caused them to gain more weight when at the end of the study they were fed a high-fat diet -- a weight gain of 50 grams in the fructose-fed rats versus 30 grams in rats fed a fructose-free diet -- according to a new study from researchers at the University of Florida College of Medicine in Gainesville, Florida, USA.

During the first six months, there was no difference in weight or food intake between the two groups.

Leptin resistance was demonstrated by the fact that food intake was reduced in in rats on a fructose-free diet when they were giving a leptin injection, but this was not the case in rats on the high-fructose diet.

Leptin is a hormone produced by fat cells that reduce appetite and, in some animals, increases metabolism. Read the entire article | Email this article
Posted by Admin2 on Thu, Oct 16, 2008 6:44 am | [0] comments

Friday, October 10, 2008

LEPTIN

Leptin deficiency alters sleep in mice, lowers metabolism during sleep

Leptin deficiency alters sleep according to research from researchers at Northwestern University in Evanston, Illinois, USA.

Leptin-deficient mice (ob/ob mice) had more arousals during sleep, and more frequent, but shorter-lasting sleep bouts, and also showed lower body temperature, in other words, lower metabolism during sleep.

They also did not recover as well from sleep deprivation when they were allowed to sleep. Read the entire article | Email this article
Posted by Admin2 on Fri, Oct 10, 2008 7:04 am | [0] comments

Monday, June 02, 2008

PRAMLINTIDE PLUS LEPTIN

Pramlintide plus leptin causes weight loss of 12.7% vs 8.4% with pramlintide and 8.2% with leptin

Obese people given two experimental drugs, pramlintide plus leptin, caused an average weight loss of 12.7 percent versus 8.4 percent in those given only pramlintide, and 8.2 percent in those only given leptin according to a study by Amylin Pharmaceuticals in San Diego, California, the company who is developing the drugs. The drugs were injected subcutaneously ( under the skin ) three times a day. The company suggests that pramlintide may help to restore leptin sensitivity which is diminished in obese people. Read the entire article | Email this article
Posted by Admin2 on Mon, Jun 02, 2008 3:18 pm | [0] comments

Wednesday, April 13, 2005

LEPTIN

Leptin nasal spray better at reducing appetite and leptin injections

Nasal administration of leptin reduced appetite in rats better than when it was injected into the gut according to anew study from Japan. Read the entire article | Email this article
Posted by Admin2 on Wed, Apr 13, 2005 4:30 am | [0] comments

Monday, April 11, 2005

LEPTIN

Stress may decrease leptin’s weight-reducing effect

Stress hormones may increase weight by interfering with the effects of leptin according to a recent study. Read the entire article | Email this article
Posted by Admin2 on Mon, Apr 11, 2005 6:55 am | [0] comments

Thursday, July 29, 2004

Ghrelin blocks the appetite-reducing effect of leptin

Ghrelin blocks the appetite-reducing effect of leptin according to a study performed on rats. Read the entire article | Email this article
Posted by Admin2 on Thu, Jul 29, 2004 3:07 pm | [0] comments

Sunday, June 20, 2004

Leptin may contribute to obesity-related cardiovascular problems

Leptin, the hormone released from fat cells discovered in 1994, that was once hoped to be a treatement for obesity, may contribute to hypertension, atherosclerosis, and an enlargement of the left pumping chamber of the heart which increases the risk of heart failure (left ventricular hypertrophy) according to a new paper from researchers at the University of Iowa. Read the entire article | Email this article
Posted by Admin2 on Sun, Jun 20, 2004 10:42 am | [0] comments

Tuesday, April 27, 2004

Leptin levels fall 50 percent during weight loss

LEPTIN LEVELS FELL 53 percent in a group of obese people who lost 10 percent of their body weight according to one study. Read the entire article | Email this article
Posted by Admin2 on Tue, Apr 27, 2004 12:12 am | [0] comments

Thursday, April 01, 2004

5-HTP increases leptin, carbidopa decreases

5-Hydroxytryptophan (5-HTP) dose-dependently increases leptin in mice, however, pretreatment with carbidopa suppresses this increase according to a study from Kobe Pharmaceutical University in Kobe, Japan. Read the entire article | Email this article
Posted by Admin2 on Thu, Apr 01, 2004 5:08 am | [0] comments
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