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DHEA: No effect on body weight or composition
Friday, August 27, 2004 12:58 am Email this article
Dehydroepiandrosterone (DHEA) does not cause weight loss or a change in body composition according to a recent study.
Thirteen morbidly obese adolescents who on average were 15.5 years old and had a body mass index (BMI) of 49 were given DHEA or placebo 40 mg sublingually twice a day for two months.
Testosterone levels increased in women, but not in men. There were no changes in weight, body composition, cholesterol levels or insulin sensitivity.
Advertisements claiming that DHEA causes weight loss are based on rodent studies, not human studies.
Vogiatzi MG, Boeck MA, Vlachopapadopoulou E, El-Rashid R, New MI. Dehydroepiandrosterone in Morbidly Obese Adolescents: Effects on Weight, Body Composition, Lipids, and Insulin Resistance. Metabolism, August 1996, 45(8):1011-5.
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