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    Thorazine plus Serentil (mesoridazine) associated with weight gain of 7 pounds after 2.5 months


    Posted by .(JavaScript must be enabled to view this email address)
    Saturday, August 28, 2004 9:26 am Email this article
    The combination of Thorazine (chlorpromazine) plus Serentil (mesoridazine) is estimated to cause an average weight gain of 7 pounds after two-and-one-half months according to a recent review paper. Weight gain NOT dose related: 375 mg per day causes gain of 7 lbs; 500 mg per day a gain of 5.4 lbs

    Weight gain is not dose related. A dose of 375 mg per day causes an average weight gain of 7 pounds after two-and-one-half months, whereas a dose of 500 mg per day causes an average weight gain of 5.4 pounds.

    Thorazine used to treat psychotic disorders

    Thorazine (chlorpromazine) is used to treat psychotic disorders and symptoms such as hallucinations, delusions, and hostility according to MedlinePlus.

    It also is used to prevent and treat nausea and vomiting, to treat behavior problems in children, and to relieve severe hiccups.

    Serentil (mesoridazine) is used to treat the symptoms of schizophrenia and reduce restlessness, anxiety, and tension.

    It also can reduce hyperactivity and uncooperativeness.

    REFERENCE(S)

    Allison D, Mentore J, Heo M, Chandler L, Cappelleri J, Infante M, Weiden P. Antipsychotic-induced weight gain: a comprehensive research synthesis. Am J Psychiatry. 1999 Nov, 156(11):1686-96.

    AUTHOR’S CONTACT INFORMATION

    D. Allison
    Obesity Research Center
    St. Luke’s-Roosevelt Hospital
    Columbia University College of Physicians and Surgeons
    New York, NY 10025, USA
    .(JavaScript must be enabled to view this email address)

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