QUICKLINKS AND VIEW OPITONS
Diet drugs: When were diet drugs approved by the FDA?
Wednesday, September 08, 2004 4:33 pm Email this article
Here are when various diet drugs were approved by the U.S. Food and Drug Administration (FDA). Phentermine, 1959
Phentermine (Adipex-P, Ionamin, Fastin, Teramine) was approved in May 1999.
Dietylpropion (Tenuate) was approved in August 1959.
Benzphetamine (Didrex) was approved in November 1960.
Fenfluramine, 1973, removed 1997
Fenfluramine (Pondimin) was approved in June 1973, and removed in September 1997 because of heart valve problems.
Mazindol (Sanorex, Mazanor) was approved in June 1973.
Phendimetrazine (Bontril), 1982
Phendimetrazine (Bontril) was approved in September 1982.
Dexfenfluramine, 1996, removed 1997
Dexfenfluramine (Redux) was approved in April 1996, and removed in September 1997 because of heart valve problems.
Meridia (sibutramine), 1997
Meridia (sibutramine) was approved in November 1997.
Xenical (orlistat), 1999
Xenical (orlistat) was approved in April 1999.
Drugs sold over-the-counter do not have formal FDA approval dates, however, ephedrine has been used since the 1960’s.
Phenylpropanolamine (PPA), 1960’s
Drugs sold over-the-counter do not have formal FDA approval dates, but phenylpropanolamine (PPA) has been used since the 1960’s, however, it was removed in in September 2000 because a study by Yale researchers concluded that PPA increased the risk of hemorrhagic stroke.
(Note: I strongly disagree with the conclusions of this study. I spent months reviewing this study as well as 300 other studies about PPA and hemorrhagic stroke, and found over 50 problems with the Yale PPA Hemorrahgic Stroke study which led to the removal of PPA, many of which were enough to negate the findings of the study. However, I have not yet published my findings.)
Stafford R, Radley D. National trends in antiobesity medication use. Arch Intern Med. 2003 May 12, 163(9):1046-50.
AUTHOR’S CONTACT INFORMATION
Stanford Center for Research in Disease Prevention
1000 Welch Road
Palo Alto, CA 94304, USA
Articles on the same subject can be found here:
On Sep 08, 2004 at 6:40 pm gn1tmac wrote:
. . . . .
2,4-Dinitrophenol (DNP) was used in the 1930's as a weight loss drug for obese individuals. The FDA banned DNP because it caused cataracts in 1% of patients treated with DNP.
On Sep 09, 2004 at 1:17 am Dr. Lu Jason wrote:
. . . . .
CAN YOU E-MAIL THE "over 50 problems with the Yale PPA Hemorrahgic Stroke study " TO ME? I VERY HOPE TO SEE IT. THANK YOU VERY MUCH!
On Sep 09, 2004 at 7:14 am Larry Hobbs wrote:
. . . . .
Thanks for you input. I appreciate it.
On Sep 09, 2004 at 7:15 am Larry Hobbs wrote:
. . . . .
Dr. Lu Jason,
I'll let you know when I publish the results.
Please feel free to share your comments about this article.
© Copyright 2003-2017 - Larry Hobbs - All Rights Reserved.