fatnews.com Fatnews Bitchute Channel Link Home page  >  Article | Previous article | Next article



  • Categories of Articles
  • Summary View
  • Headline View
  • Archive of Quotes
  • Contact Us
  • Glutamine potently stimulates release of GLP-1 which might cause weight loss

    Posted by .(JavaScript must be enabled to view this email address)
    Monday, September 20, 2004 3:50 pm Email this article
    The amino acid glutamine potently releases a peptide in the gut which reduces food intake called glucagon-like peptide-1 (GLP-1) according to a new study. GLP-1 reduces food intake and body weight

    Studies have found that GLP-1 reduce hunger, calorie intake and bodyweight in both normal and type 2 diabetics (Meier et al, 2002).

    Glutamine increases GLP-1, 7-fold

    In the current study, an optimal dose of glutamine increased GLP-1 release by 7.1-fold.

    Glutamine more potent than glucose or other amino acids

    Glutamine was a more potent at releasing GLP-1 than glucose or other amino acids.

    Conclusion: Glutamine might be useful for treating diabetes and obesity

    “The results suggest that nutritional agents like glutamine might have beneficial effects in diabetes and obesity,” the authors of the study concluded.

    GLP-1 also has an anti-diabetic effect (Meier et al, 2002).

    Previous study in mice found glutamine caused weight loss in mice

    A previous study found that glutamine reduced blood sugar, insulin, and caused weight loss in mice.

    Previous study found 2 grams of glutamine increased growth hormone 4-fold

    A previous study also found that giving people 2 grams of glutamine orally increased growth hormone levels by an average of 4-fold (Welbourne, 1995).

    Waiting for human weight loss studies

    I am not aware of any human studies testing the effect of glutamine on weight loss in humans.


    Reimann F, Williams L, Da Silva Xavier G, Rutter G, Gribble F. Glutamine potently stimulates glucagon-like peptide-1 secretion from glutag cells. Diabetologia. 2004 Sep 9.


    F. Reimann
    Cambridge Institute for Medical Research
    Wellcome Trust/MRC Building
    Addenbrooke’s Hospital
    Hills Road
    CB2 2XY, Cambridge, UK


    Meier J, Gallwitz B, Schmidt W, Nauck M. Glucagon-like peptide 1 as a regulator of food intake and body weight: therapeutic perspectives. Eur J Pharmacol. 2002 Apr 12, 440(2-3):269-79.


    J. Meier
    Medizinische Klinik I
    St. Josef-Hospital
    Klinikum der Ruhr-Universitat Bochum
    Gudrunstr. 56, Germany


    Welbourne T. Increased plasma bicarbonate and growth hormone after an oral glutamine load. Am J Clin Nutr. 1995 May, 61(5):1058-61.


    T. Welbourne
    Department of Physiology
    Louisiana State University College of Medicine
    Shreveport 71130, USA

    Articles on the same subject can be found here:


    Please feel free to share your comments about this article.




    Please enter the word you see in the image below:

    Remember my personal information

    Notify me of follow-up comments?

    © Copyright 2003-2021 - Larry Hobbs - All Rights Reserved.