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U.S. NIH’s Obesity Guidelines Part 20: Weight loss lowers blood pressure
Wednesday, December 15, 2004 3:12 am Email this article
A weight loss of 22 pounds induced by lifestyle changes lowers systolic blood pressure an average of 7 points, and diastolic blood pressure 3 points according to a 1987 meta-analysis of five studies of hypertensive patients. (p. 29) Ten pound weight loss effect on blood pressure equal to antihypertensive drugs
A weight loss of 10.4 pounds was associated with a reduction 2.8 points in systolic blood pressure and 2.5 points in diastolic blood pressure according to one study.
Among patients who lost at least 9.9 pounds, the effect of weight loss on blood pressure was equivalent to antihypertensive medications. (p. 29)
Nine pound weight loss reduces cardiovascular complications, etc from 39% to 26% in older people
A weight loss of at least 9 pounds reduced the incidence of hypertension, taking antihypertensive medication, or having a cardiovascular complication to 26 percent of people ages 60- to 80-years-old compared to 39 percent in those who lost less. (p. 30)
Weight loss of 2 lbs reduces blood pressure 0.4 / 0.3 points
Another study found that a weight loss of 2.2 pounds was associated with a systolic reduction of 0.4 mm Hg and a diastolic reduction of 0.3 mm Hg in men not taking antihypertensive medications. The effect was slightly less in men taking antihypertensive medications. (p. 30)
One study reported 7 lbs loss had no effect on blood pressure
Only one controlled study has report that weight loss, an average of 7.3 pounds, had no effect on blood pressure. Another study reported blood pressure fell only in patients who reduced their sodium intake.
22 lbs loss reduces systolic 6-7 points, diastolic 4-6 points
Weight loss also reduces blood pressure in patients without hypertension.
One study found that a weight loss of 22 pounds was associated with a 7 point reduction in systolic blood pressure after a year-and-a-half and 6 points after three years.
Diastolic blood pressure fell 5-6 points and 4 points, respectively.
Weight loss reduced the incidence of hypertension 20-50 percent after 1.5 years, and 19 percent after three years. (p. 31)
4 lbs loss lowered blood pressure 4 points in black diabetics
In a study of older black diabetic patients a weight loss of 5.3 pounds lowered both systolic and diastolic blood pressure approximately 4 mm Hg. (p. 31)
20 lb weight loss had no effect on blood pressure after 9 months in non-hypertensives
In another study of non-hypertensives weight loss was associated with a reduction in blood pressure after three months, but not after nine months despite a weight loss of 19.8 pounds. (p. 31)
Weight loss from most diet drugs lowers blood pressure
Blood pressure is reduced by a similar amount in patients who lose weight with the help of weight loss medications compared to those who lose weight with a placebo. However, this is not true with Meridia (sibutramine). (p. 32)
Meridia weight loss: Blood pressure increases in half of patients, falls in one-third
Meridia is associated with an average increase of 1-3 mm Hg in systolic blood pressure, and 1-2 mm Hg increase in diastolic pressure.
At the recommended doses of Meridia, 45 percent of patients had an increase in blood pressure, 35 percent had a decrease, and 20 percent had no change.
Xenical weight loss: Blood pressure reduced 1-2 points
Xenical? (orlistat)-induced weight loss was associated with a 2 point reduction in systolic blood pressure and a 1 point reduction in diastolic.
No long term studies with other diet drugs to determine effect on blood pressure
No long-term studies using other weight loss medicines such as phentermine, diethylpropion, mazindol, phenylpropanolamine, or ephedrine and caffeine were available for analysis of their effect on blood pressure.
Reducing belly fat may lower blood pressure
A reduction in abdominal fat is associated with a reduction in blood pressure, however, this has not been shown to be independent of weight loss. (p. 32)
Exercise reduces blood pressure
Aerobic exercise lowers blood pressure independent of weight loss. (p. 32)
Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults : the evidence report / National Heart, Lung, and Blood Institute [Bethesda, Md.] : National Institutes of Health, National Heart, Lung, and Blood Institute, . NIH publication No. 98-4083.
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