Xenical (orlistat) reduces the risk of diabetes by 37%, Metformin by 31%, Precose (acarbose) by 25%

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Wednesday, March 09, 2005 9:02 am Email this article
Being overweight increases the risk of type 2 diabetes more than any other disease. Xenical (orlistat) reduces the risk of diabetes over a two-to-four year period by 37 percent according to paper from Canada.

Other drugs that reduce the risk of diabetes are as follows:

• Glucophage (metformin) reduces the risk by 31 percent
• Precose (acarbose) reduces the risk by 25 percent
• Rezulin (troglitazone) reduces the risk by 55 percent (Rezulin was removed from the U.S. market in 2000 because of potentially fatal liver problems associated with the drug).

REFERENCE

Padwal R, Majumdar S, Johnson J, Varney J, Mcalister F. A systematic review of drug therapy to delay or prevent type 2 diabetes. Diabetes Care. 2005 Mar, 28(3):736-744.

AUTHOR’S CONTACT INFORMATION

R. Padwel
Department of Medicine
2E3.22 Walter C. Mackenzie HSC
University of Alberta Hospital
8440-112th St.
Edmonton, AB, Canada, T6G 2B7
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Articles on the same subject can be found here:

• Acarbose (Precose)

• Diabetes

• Glucophage (metformin)