QUICKLINKS AND VIEW OPITONS
Chitosan reduces fat by less than 3 calories per day
Monday, March 28, 2005 7:21 am Email this article
Chitosan does not block fat absorption according to a recent study from researchers at Hoffman-La Roche, the makers of the fat-blocking drug Xenical® (orlistat). 3 grams of chitosan per day only blocks 3 fat calories per day
Approximately 1 gram of chitosan (1,000 mg) given three times per day (3,000 mg per day) increased fat excretion by less than 3 calories per day compared to 145 calories per day when the same subjects were given a standard dose of Xenical (120 mg three times per day).
Subjects: 7 men, 5 women, 1 week
The study included seven men and five women ages 18- to 45-years-old who lived in a research facility during the study and were given each compound for a week while being feed a 2500 calorie 30 percent fat diet.
Chitosan is a fiber
Chitosan is a fiber made from the hard outer skeletons of shellfish and insects.
Previous study: 2,000 mg per day blocked 10 calories per day
A previous study found that 1 gram of chitosan (1,000 mg) given twice a day (2,000 mg per day) increased fecal fat excretion by a mere 10 calories per day.
Previous study: 4,000 mg per day caused no weight loss
Another study found that 2 grams of chitosan (2,000 mg) given before lunch and before dinner (4,000 mg per day) did not cause weight loss.
Huge doses might be necessary for weight loss
In January 1997 I wrote “There are no human studies and only a couple animal studies suggesting that chitosan may cause weight loss. The required dose for humans may be 15 grams per day [15,000 mg] combined with vitamin C… I think I’ll save my money.”
And in September 1998 I wrote “This means that chitosan is 99 percent less effective than the infomercial is claiming and would only block 1 pound of fat per year! I wonder if the Federal Trade Commission will eventually stopped them.”
FTC stopped an informercial selling chitosan
Well, the FTC did stopped them.
Enforma Natural Products Inc. which sold the chitosan-based Enforma System via television infomercial agreed in April 2000 to pay the U.S. Federal Trade Commission (FTC) $10 million and said that it would no longer make deceptive weight loss claims.
The FTC is also dued the host of the program, former baseball player Steve Garvey for making “false and unsubstantiated” claims.
Lark Kendall, a co-host of the infomercial, already reached a settlement and agreed to surrender her talent fee for appearing on the program.
Anyone who purchased The Enforma System could get a refund by completing the forms at the FTC’s website http://www.ftc.gov or by calling (202) 326-3123.
Guerciolini R; Radu-Raduleseu L; Boldrin M; Dallas J; Moore RF. Comparative evaluation of fecal fat excretion induced by orlistat and chitosan. International Journal of Obesity, May 2000, 24 (Suppl 1), S167 (abstract 563).
Articles on the same subject can be found here:
On Mar 30, 2005 at 2:13 am Randy Smith, MD wrote:
. . . . .
I have not been impressed with chitosan for weight loss either. There is a dietary supplement called 'cassia nomame' that functions as a lipase inhibitor for those who want to avoid pharmaceuticals.
This of course will be banned after Aug 1st, 2005 along with most other dietary supplements if the FTAA passes and we become harmonized with the EU according to the CODEX plan.
Randy Smith, MD
On Mar 30, 2005 at 3:40 am Larry Hobbs wrote:
. . . . .
Thank you for your input.
I am not familiar with cassia nomame.
Green tea and oolong tea also inhibit pancreatic lipase, the key enzyme required for the absorption of dietary fats, in a dose-dependent manner, that is, the more green or oolong tea consumed, the more the enzyme was inhibited.
However, the pancreatic lipase-inhibiting substance has not been identified.
It was determined that the pancreatic lipase-inhibiting substance was not caffeine, nor was it any of the tea tannins such as epicatechin, epigallocatechin (EGC), epicatechin gallate (ECG) and epigallocatechin gallate (EGCG).
Green tea and oolong tea also increase the release of fat from fat cells and increase the amount of fat that is burned.
The increase in fat release from fat cells was determined to be the result of the caffeine in the tea.
Articles on tea can be found here:
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