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    Isomerized hop extract increases fat excretion, reduces weight gain in mice

    Posted by .(JavaScript must be enabled to view this email address)
    Thursday, April 28, 2005 5:38 am Email this article
    Isomerized hop extract, a natural product required in the beer brewing process, reduced weight gain in mice fed a high-fat diet according to a new study. Inhibits pancreatic lipase, same as Xenical

    The product seems to work by inhibiting pancreatic lipase, the key enzyme required for digestion and absorption of dietary fat.

    Xenical inhibits same enzyme

    This action is the same as the prescription diet pill Xenical (orlistat).

    So do green tea and oolong tea

    Green tea and oolong tea also inhibit this enzyme.

    Isomerized hop extract increases fat excretion

    Mice given the compound showed reduced levels of fat in their blood (triglycerides) and excreted more fat in their stool.

    Consists mainly of isohumulones

    Isomerized hop extract consists mainly of isohumulones.


    Yajima H, Noguchi T, Ikeshima E, Shiraki M, Kanaya T, Tsuboyama-Kasaoka N, Ezaki O, Oikawa S, Kondo K. Prevention of diet-induced obesity by dietary isomerized hop extract containing isohumulones, in rodents. Int J Obes Relat Metab Disord. 2005 Apr 19.


    Central Laboratories for Key Technology
    Kirin Brewery Co., Ltd
    Kanagawa, Japan

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