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    Zyprexa (olanzapine) dose of 13.3 mg per day or more increases risk of large weight gain 3-fold


    Posted by .(JavaScript must be enabled to view this email address)
    Monday, May 09, 2005 6:01 am Email this article
    The antipsychotic drug Zyprexa (olanzapine) is associated with weight gain. The typical dose is 5 to 20 mg per day. A dose of 13.3 mg per day or more increases the risk of a large weight gain 3-fold.

    Large weight gain is defined as gaining 7 percent or more of body weight.

    REFERENCE

    Perry P, Argo T, Carnahan R, Lund B, Holman T, Ellingrod V, Miller D. The association of weight gain and olanzapine plasma concentrations. J Clin Psychopharmacol. 2005 Jun, 25(3):250-54.

    AUTHOR’S CONTACT INFORMATION

    Department of Clinical and Administrative Pharmacy
    College of Pharmacy
    University of Iowa
    Iowa City, IA, USA

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