Zyprexa (olanzapine) dose of 13.3 mg per day or more increases risk of large weight gain 3-fold

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Monday, May 09, 2005 6:01 am Email this article
The antipsychotic drug Zyprexa (olanzapine) is associated with weight gain. The typical dose is 5 to 20 mg per day. A dose of 13.3 mg per day or more increases the risk of a large weight gain 3-fold.

Large weight gain is defined as gaining 7 percent or more of body weight.

REFERENCE

Perry P, Argo T, Carnahan R, Lund B, Holman T, Ellingrod V, Miller D. The association of weight gain and olanzapine plasma concentrations. J Clin Psychopharmacol. 2005 Jun, 25(3):250-54.

AUTHOR’S CONTACT INFORMATION

Department of Clinical and Administrative Pharmacy
College of Pharmacy
University of Iowa
Iowa City, IA, USA

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• Zyprexa (olanzapine)