180 to 720 mg of rubidium chloride had a significant antidepressant effect in two-thirds of patients

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Tuesday, May 24, 2016 5:39 pm Email this article

Thirty-one female patients hospitalized for depression were given from 180 to 720 mg of rubidium chloride per day.

“By week 2, at least two-thirds had improved significantly” the paper notes.

Adverse Effects: Diarrhea, Increase Urine, Excitement

Side effects included diarrhea, polyuria (producing abnormally large volumes of urine), and excitement, but were generally mild and rarely required interruption of the trial.

Note:

Reference

Placidi G, Lenzi A, Lazzerini F, Dell’Osso L, Cassano GB, and Akiskal HS. Exploration of the clinical profile of rubidium chloride in depression: a systematic open trial. J Clin Psychopharmacol, 1988 Jun; 8(3): 184-188.

Author’s Contact Info

Institute of Clinical Psychiatry,
University of Pisa, Italy

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• Antidepressants

• Depression

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