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Phendimetrazine: 70 mg three times per day causes 15% weight loss after three months
Monday, February 13, 2006 10:15 am Email this article
Patients given 70 mg of phendimetrazine three times per day an hour before meals lost an average of 14.7 percent of body weight in three months without dietary restriction or behavior modification. (Cass, 1961) Weight loss continued for entire 3 months
Weight loss was steady throughout the three months and patients appeared to be still be losing at the end of the study although the authors of the study stated that tolerance tends to develop at about this time.
Patients were not asked to diet or exercise
Again, patients in this study were not given any specific dietary recommendations. In other words, there were not told to reduce their calorie intake.
This was done in order to isolate the effect of the drug.
All diet pill studies were done this way back in the 1960’s
Note: This study was performed in 1961. Back then, this is the way that studies were done. Subjects were simply givent the diet drug but were not asked to diet and exercise. It wasn’t until twenty or thirty years ago, that diet pill studies started asking patients to diet and exercise as well.
Cass LJ. Evaluation of phendimetrazine bitartrate as an appetite suppressant. Canadian Medical Association Journal, 1961 May 20;84:1114-6.
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