Topmax reduces binge eating and causes weight loss of 9.9 lbs

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Wednesday, June 06, 2007 2:02 am Email this article
Topmax (topiramate) slightly reduces binge eating and causes an average weight loss of 9.9 pounds in binge eaters according to a study from researchers at the University of Cincinnati College of Medicine in Cincinnati, Ohio. Weight Loss

Weight Loss: -9.9 lbs vs +0.4 lbs

Binge eaters who were given Topamax (topiramate) lost an average of 9.9 pounds versus a weight gain of 0.4 pounds for those given a placebo.

 

Binge Episodes

5 fewer bingeing episodes per week vs 3.4 fewer

Those given Topmax had 5 fewer binge eating episodes per week compared to 3.4 fewer episodes for those given a placebo.

 

Bingeing in Remission

Bingeing elminated in 58% of patients vs 29%

Topmax eliminated binge eating in 58 percent of patients versus 29 percent who were given placebo.

 

Side Effects

Side Effects: Skin sensations, upper respiratory tract infection, drowsiness, and nausea

The most common side effects with Topmax were paresthesia (unusual skin sensations), upper respiratory tract infection, somnolence (drowsiness), and nausea.

REFERENCE

Mcelroy S, Hudson J, Capece JA, Beyers K, Fisher AC, Rosenthal N. Topiramate for the treatment of binge eating disorder associated with obesity: A placebo-controlled study. Biol Psychiatry. 2007 May 1, 61(9):1039-48.

AUTHOR’S CONTACT INFORMATION

Susan McElroy
Psychopharmacology Research Program
Department of Psychiatry
University of Cincinnati College of Medicine
Cincinnati, Ohio 45267-0559, USA
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Articles on the same subject can be found here:

• Binge Eating

• Topamax (topiramate)