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  • Topmax reduces binge eating and causes weight loss of 9.9 lbs

    Posted by .(JavaScript must be enabled to view this email address)
    Wednesday, June 06, 2007 2:02 am Email this article
    Topmax (topiramate) slightly reduces binge eating and causes an average weight loss of 9.9 pounds in binge eaters according to a study from researchers at the University of Cincinnati College of Medicine in Cincinnati, Ohio. Weight Loss

    Weight Loss: -9.9 lbs vs +0.4 lbs

    Binge eaters who were given Topamax (topiramate) lost an average of 9.9 pounds versus a weight gain of 0.4 pounds for those given a placebo.


    Binge Episodes

    5 fewer bingeing episodes per week vs 3.4 fewer

    Those given Topmax had 5 fewer binge eating episodes per week compared to 3.4 fewer episodes for those given a placebo.


    Bingeing in Remission

    Bingeing elminated in 58% of patients vs 29%

    Topmax eliminated binge eating in 58 percent of patients versus 29 percent who were given placebo.


    Side Effects

    Side Effects: Skin sensations, upper respiratory tract infection, drowsiness, and nausea

    The most common side effects with Topmax were paresthesia (unusual skin sensations), upper respiratory tract infection, somnolence (drowsiness), and nausea.


    Mcelroy S, Hudson J, Capece JA, Beyers K, Fisher AC, Rosenthal N. Topiramate for the treatment of binge eating disorder associated with obesity: A placebo-controlled study. Biol Psychiatry. 2007 May 1, 61(9):1039-48.


    Susan McElroy
    Psychopharmacology Research Program
    Department of Psychiatry
    University of Cincinnati College of Medicine
    Cincinnati, Ohio 45267-0559, USA
    .(JavaScript must be enabled to view this email address)

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