Increasing body weight associated with lower PSA levels

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Wednesday, July 25, 2007 4:38 am Email this article
Higher body weights are associated with lower prostate-specific antigen (PSA) levels according to a study from Paris, France. PSA Levels

PSA levels according to BMI

Average PSA levels were as follows:

• Normal weight - BMI 25 or less: PSA 3.7
• Overweight - BMI 25-30: PSA 2.9
• Obese - BMI 30-35: PSA 2.6
• Very obese - BMI 35 or more: PSA 1.5

 

Fat Increases Estrogen

This may be because fat increases estrogen

This may be because fat cells produce estrogen which counter testosterone which increases PSA levels.

 

Conclusion

Conclusion: PSA levels lower as BMI increases

“PSA is lower as BMI increases,” the authors concluded.

The researchers suggested that acceptable levels of PSA should depend on BMI.

 

PSA Defined

PSA defined: Increasing levels associated with prostate cancer

Prostate-specific antigen (PSA) is a protein produced by the prostate gland.

Increasing levels of PSA levels are indicative of prostate cancer.

REFERENCE

Larre S, Azzouzi A, Cancel-Tassin G, Cormier L, Villette J, Hoffmann P, Drelon I, Baschet F, Mangin P, Cussenot O. [Impact of obesity on psa in prostate cancer screening]. Prog Urol. 2007 Jun, 17(4):815-18.

AUTHOR’S CONTACT INFORMATION

Stephane Larre
Centre de Recherche pour les Pathologies Prostatiques (CeRePP)
EA3104 Universite Paris 7
UFR Biomedicales des Saint-Peres
Paris, France
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