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Acomplia (rimonabant) causes an average weight loss of 10.3 pounds more than placebo
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Friday, November 16, 2007 10:39 am Email this article
Acomplia (rimonabant) causes an average weight loss of 10.3 pounds more than placebo according to an analysis by researchers from the University of Alberta in Edmonton, Alberta, Canada. Side Effects
Psychiatric side effects such as depression in 6% of patients
“The most worrying adverse effect was an increased incidence of psychiatric disorders (depression, anxiety, irritability, aggression), which occurred in 6% of patients receiving rimonabant,” the researchers noted.
Subjects
Subjects: 6365 people
The analysis included data from 4 studies lasting one year which included a total of 6365 people.
REFERENCE
Rucker D, Padwal R, Li SK, Curioni C, Lau DCW. Long term pharmacotherapy for obesity and overweight: Updated meta-analysis. BMJ. published online 2007 Nov 15.
AUTHOR’S CORRESPONDENCE
Raj Padwal
Assistant Professor
Department of Medicine
University of Alberta
Edmonton, AB
Canada
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