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    ‘I gained 70 lbs while taking Zyprexa,’ said P. Wagner, ‘but stopped eating on Geodon plus Abilify’

    Posted by .(JavaScript must be enabled to view this email address)
    Thursday, December 27, 2007 8:38 pm Email this article
    Here is a fascinating story about a person named P. Wagner who who could not stop eating when taking Zyprexa and gained 70 pounds, but then lost a tremendous amount of weight when switched to Geodon combined with Abilify. Gained 70 lbs

    Gained 70 lbs on Zyprexa

    “I took 15-40 mg of Zyprexa (olanzapine) from 1996-2003 and gained nearly 70 pounds.

    “Although I had always been thin, I found I simply could not stop eating.

    “I was not actually hungry in the sense of hunger pangs, so much as that I was beset by “food-seeking behavior”—I simply had an uncontrollable need to eat until I had consumed a certain number of calories, at which point a swtich in my brain seemed to turn to “off” and I could stop.



    Cholesterol increased from 170 to 274, triglycerides in the 300’s

    “My cholesterol, normally 170, went to 274 and my triglycerides were in the 300’s.


    Lost Weight on Geodon plus Abilify

    Switched to Geodon plus Abilify and lost weight

    “Then I switched to Geodon combined with Abilify in 2003.

    “Now I gradually but steadily lost a great deal of weight, eventually, by 2005, weighing in at 95 lbs (I’m 5’3” tall).


    No Appetite on Geodon plus Abilify

    Appetite disappeared on Geodon plus Abilify

    “My appetite almost completely disappeared, in fact, so that my problem was that I would forget to eat more often than not and my doctor was concerned that I had developed an eating disorder.


    Started Taking Tiny Dose of Zyprexa

    Added 2.5 mg of Zyprexa to help concentrate and read

    “Abilify was effective in many respects but because I was unable to concentrate well enough to read, so I decided to accept taking a tiny dose of Zyprexa again.

    “I take only 2.5 mg [of Zyprexa], and have done for about 2 months, with a noticeable increase in my appetite, even at that low dose.


    Gained Weight with Zyprexa

    Have gained 5-8 lbs since adding Zyprexa

    “I no longer forget to eat and I have gained at least 5-8 pounds, but the benefit is that I can in fact read and write.

    “It remains to be seen if I can keep the weight gain to just those 8 pounds and go no higher.

    “If so, then the 2.5 mg is worth it.


    Zyprexa—Is It Worth It?

    Zyprexa : ‘The miracle drug from hell?’

    “If I keep gaining, then once again, Zyprexa will have proven to be the miracle drug from hell.


    Abilify Key to Appetite Control?

    Zyprexa and Abilify may help explain appetite

    “I think these two drugs, Abilify and Zyprexa may hold some key to appetite control and why people eat, overeat and gain weight.

    “They ought to be studied for their effects on the mind and appetite alone.

    “I felt absolutely driven to eat on Zyprexa, and just as certain I could not eat on Abilify, yet I was one and the same person, merely affected by two different drugs, proving that something was going on, something was changing my internal environment, so to speak, in a way that was significant and might be so for others.”


    P. Wagner’s story was first posted as a comment here:



    Articles on the same subject can be found here:


    On Sep 30, 2008 at 10:45 am jen wrote:

    . . . . .

    How much Geodon and Abilify are you taking?

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