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Saccharin does not increase the risk of bladder cancer
Tuesday, February 26, 2008 7:46 am Email this article
Saccharin does not increase the risk of bladder cancer as was once believed in the 1970's. This according to a 1998 study from the National Cancer Institute in Bethesda, Maryland, USA.
20 monkeys fed large daily doses for 24 years
Twenty monkeys of three species that were fed 5 to 10 times the normal human dose, or 11 mg per pound of body weight, five days per week, starting at birth for up to 24-years-old.
No Evidence of Cancer
No evidence of cancer with saccharin use
Researchers found no effect on urine, on cell proliferation, and no evidence of formation of solid material in the urine.
Sixteen monkeys served as controls.
Populations studies have come the same conclusion
Numerous epidemiologic studies have come to the same conclusion.
Still Listed as Possible Carcinogen
Saccharin still listed as possible carcinogen by U.S. government
Despite the evidence of its safety, the U.S. government voted in 1997 to keep saccharin on the list of possible carcinogens.
Takayama S, Sieber S, Adamson R, Thorgeirsson U, Dalgard D, Arnold L, Cano M, Eklund S, Cohen S. Long-term feeding of sodium saccharin to nonhuman primates: Implications for urinary tract cancer. J Natl Cancer Inst. 1998 Jan 7, 90(1):19-25.
AUTHOR’S CONTACT INFORMATION
Division of Basic Sciences
National Cancer Institute
Bethesda, MD 20892, USA
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