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    Saccharin does not increase the risk of bladder cancer


    Posted by .(JavaScript must be enabled to view this email address)
    Tuesday, February 26, 2008 7:46 am Email this article
    Saccharin does not increase the risk of bladder cancer as was once believed in the 1970's. This according to a 1998 study from the National Cancer Institute in Bethesda, Maryland, USA.
    Study

    20 monkeys fed large daily doses for 24 years

    Twenty monkeys of three species that were fed 5 to 10 times the normal human dose, or 11 mg per pound of body weight, five days per week, starting at birth for up to 24-years-old.

     

    No Evidence of Cancer

    No evidence of cancer with saccharin use

    Researchers found no effect on urine, on cell proliferation, and no evidence of formation of solid material in the urine.

    Sixteen monkeys served as controls.

     

    Populations Studies

    Populations studies have come the same conclusion

    Numerous epidemiologic studies have come to the same conclusion.

     

    Still Listed as Possible Carcinogen

    Saccharin still listed as possible carcinogen by U.S. government

    Despite the evidence of its safety, the U.S. government voted in 1997 to keep saccharin on the list of possible carcinogens.

    REFERENCE

    Takayama S, Sieber S, Adamson R, Thorgeirsson U, Dalgard D, Arnold L, Cano M, Eklund S, Cohen S. Long-term feeding of sodium saccharin to nonhuman primates: Implications for urinary tract cancer. J Natl Cancer Inst. 1998 Jan 7, 90(1):19-25.

    AUTHOR’S CONTACT INFORMATION

    Division of Basic Sciences
    National Cancer Institute
    Bethesda, MD 20892, USA

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