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Amisulpiride causes 3-6 pound weight gain
Saturday, September 13, 2003 3:55 pm Email this article
The anti-psychotic drug amisulpiride (not available in the U.S.) causes an average weight gain of 3 to 6 pounds according to a recently published review paper about the weight gaining potential of anti-psychotic drugs.
Low-dose amisulpride (100 mg per day) caused an average weight gain of 3.1 pounds in a medium-term study.
In a six month study patients taking 5 to 20 mg of olanzapine per day gained an average of 5.9 pounds compared to a weight gain of 2 pounds for those taking taking 200 to 800 mg of amisulpride per day.
Another study found that patients who had gained weight and developed diabetes while taking clozapine lost an average of 9.2 pounds over a ten month period with the addition of quetiapine (Seroquel), another drug used to treat psychotic disorders and symptoms such as hallucinations, delusions, and hostility.
Amisulpiride is chemically related to sulpiride, a drug which can cause weight gain.
Tardieu S, Micallef J, Gentile S, Blin O. Weight gain profiles of new anti-psychotics: public health consequences. Obes Rev. 2003 Aug, 4(3):129-38.
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