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  • 360-720 mg of rubidium chloride per day for 2 months had rapid antidepressant action in 20 people

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    Tuesday, May 24, 2016 5:17 pm Email this article

    A dose of 360 to 720 mg of rubidium chloride per day given for 60 days “showed a marked and rapid anti-depressive action” in 18 females and 2 males with major depression according to a 1993 study from Italy.

    Subjects Average Age: 55

    The patient’s average age was 55-years-old.

    Improvements in both Anxiety and Depression

    There was a gradual and significant improvement in both depression and anxiety.

    Adverse Effects: Diarrhea and Skin Rashes

    Slight adverse effects that were observed included diarrhea and skin rashes.


    “Rubidium chloride showed a marked and rapid anti-depressive action which was particularly evident in relation to mood, anti-conservative ideas, work, occupational interests and psychomotory slowing-down,” the abstract notes.

    Note: I do not have a copy of the paper, which is in Italian, so I can only tell you what is in the abstract.


    Torta R, Ala G, Borio R, Cicolin A, Costamagna S, Fiori L, and Ravizza L. [Rubidium chloride in the treatment of major depression]. Minerva Psichiatr, 1993 Jun; 34(2): 101-110.

    Author’s Contact Info

    Istituto di Clinica Psichiatrica
    Universita degli Studi di Torino
    [University in Turin, Italy]


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