Women taking a diuretic pus an ACE Inhibitor were 12% MORE likely to die of cardiovascular disease

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Monday, August 31, 2009 7:32 am Email this article

Women taking a diuretic plus an ACE inhibitor were 12% more likely to die of cardiovascular disease during a 5.9 year follow-up than women taking NO blood pressure medicines even though the average systolic pressure was 16 points LOWER in the drug group than the no drug group (133 mm Hg vs 149 mm Hg) according to a 2004 study.

To say this the other way, women taking NO blood pressure drugs were 11% LESS likely to die of cardiovascular disease during a 5.9 year follow-up than women taking a diuretic plus an ACE inhibitor.

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REFERENCE

Wassertheil-Smoller S, Psaty B, Greenland P, Oberman A, Kotchen T, Mouton C, Black H, Aragaki A, Trevisan M. Association between cardiovascular outcomes and antihypertensive drug treatment in older women. JAMA. 2004 Dec 15, 292(23):2849-59.

AUTHOR’S CONTACT INFORMATION

Sylvia Wassertheil-Smoller, PhD
Professor and Division Head, Department of Epidemiology & Population Health
Principal Investigator, Women’s Health Initiative
Albert Einstein College of Medicine
Department of Epidemiology and Population Health
1300 Morris Park Avenue
Belfer Building, Room 1312
Bronx, NY 10461
718-430-2358 phone
718-430-2359 phone
718-430-3076 fax
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http://www.aecom.yu.edu/home/faculty/profile.asp?id=5563

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