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Tofranil (imipramine) caused an average weight gain of 10 lbs in one year
Friday, October 02, 2009 7:45 pm Email this article
Patients given Tofranil (imipramine) for panic disorder gained an average of 9.9 pounds or 5.7 percent of body weight after one year according to a recent paper. Body Weight
Body Weight Gain
The average body weight of patients increased from 172.5 lbs to 182.4 lbs.
Two of the eighteen patients (11%) did not gain or lose weight.
Three of the eighteen patients (17%) gained less than 5 percent of their body weight.
Thirteen of the eighteen patients (72%) gained more than 5 percent of their body weight.
Average dose 160 mg per day
The average dose of the drug used was 160 mg per day.
Mavissakalian M, Perel J, Guo S. Specific side effects of long-term imipramine management of panic disorder. J Clin Psychopharmacol. 2002 Apr, 22(2):155-61.
AUTHOR’S CONTACT INFORMATION
Matig Mavissakalian, MD
Anxiety Disorders Program
University Hospitals of Cleveland
11100 Euclid Avenue
Cleveland, OH 44106, USA
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