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Disruption of our circadian rhythm ‘has a direct role in inducing accelerated aging’
Monday, December 13, 2010 12:47 pm Email this article
"The incidence and progression of some types of cancer, such as breast, endometrial, prostate, colorectal and melanoma, can be promoted by" disruption of our natural circadian rhythm, called chronodisruption, according to a recent paper by researchers at the University of Murcia in Murcia, Spain. Cancer
Disruptions in circadian rhythms may play a role in the initiation and development of cancer
“Both human epidemiological and experimental studies of animals have documented that a potential negative consequence of [chronodisruption] is cancer initiation and development,” the authors note.
“In addition, a relation between [chronodisruption] and cancer prognosis has been observed in humans.
“In metastatic colorectal cancer patients, marked rest–activity rhythms are associated with a better quality of life, better response to chemotherapy and longer survival,” the authors conclude.
Garaulet M, Ordovas J, Madrid J. The chronobiology, etiology and pathophysiology of obesity. Int J Obes (Lond). 2010 Jun 22, published on-line.
AUTHOR’S CONTACT INFORMATION
Dr M Garaulet
Faculty of Biology, Department of Physiology
University of Murcia, Faculty of Biology
Campus of Espinardo
Murcia 30100, Spain
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