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  • An unfortunate resurgence of HCG use for weight loss


    Posted by .(JavaScript must be enabled to view this email address)
    Thursday, April 26, 2012 12:44 pm Email this article
    "Given that hCG has no demonstrated weight loss effects and has potential safety concerns, it is incumbent upon the scientific and clinical community in the obesity field to educate their patients about the lack of efficacy and potential risks of off-label hCG use and to speak out strongly against its use," writes Jennifer Lovejoy, PhD in a recent letter to the editor published in the International Journal of Obesity.

    HCG for weight loss started in 1954

    Giving HCG for weight loss started in 1954

    “Some 55 years ago, English physician ATW Simeons proposed to treat obesity by administering human chorionic gonadotropin (hCG). Simeons’ protocol involves a combination of up to 6 weeks of a daily low-dose hCG injection and a very-low-calorie-diet (500kcal per day).

    HCG no better than a placebo

    HCG no better than a placebo in several randomized studies

    “Early hCG clinical trials showed mixed results for weight loss; however, in recent decades several randomized controlled trials demonstrated that hCG was no better than placebo, and experts concluded that hCG has no merit for weight loss.”

    HCG should be discouraged

    Doctors should discourage the use of HCG for weight loss

    “Thus, the use of hCG for weight loss is discouraged by legitimate clinicians who treat obese patients.”

    Weight loss is due to the 500 calories diet, NOT the HCG

    The weight loss is due to the 500 calories diet, NOT the HCG

    “Anecdotal stories indicate that many patients are satisfied with these programs because of the success of weight loss, although any weight loss that occurs is very likely due to the hypocaloric diet rather than any effect of hCG per se and as there is usually no weight loss maintenance program provided, weight is quickly regained after the end of the program.”

    Safety Concerns

    Safety concerns with HCG

    “A typical dosage used for weight loss programs is the daily dosage of 150 IU for six times per week or weekly dosage of 1000 IU.

    HCG might increase the risk of pregnancy, Lovejoy notes.

    HCG might also exacerbate endometriosis.

    HCG might also increase the risk of an enlarged prostate, prostate cancer, breast enlargement in men, and breast cancer in men.

    Safety Concerns

    Safety concerns with HCG

    “Given that hCG has no demonstrated weight loss effects and has potential safety concerns, it is incumbent upon the scientific and clinical community in the obesity field to educate their patients about the lack of efficacy and potential risks of off-label hCG use and to speak out strongly against its use,” Dr. Lovejoy concludes.

    REFERENCE

    Lovejoy J, Sasagawa M. An unfortunate resurgence of human chorionic gonadotropin use for weight loss. Int J Obes (Lond). 2011 Oct 4, JC Lovejoy
    Alere Wellbeing, Inc. and University of Washington
    School of Public Health
    Seattle, WA, USA
    .(JavaScript must be enabled to view this email address)

    M Sasagawa
    University of Washington School of Nursing
    Department of Psychosocial & Community Health
    Seattle, WA, USA
    .(JavaScript must be enabled to view this email address)

    Other articles

    Other articles about HCG

    Articles on the same subject can be found here:


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