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  • Herbal anti-obesity powder (Codonopsis Eupolyphaga) causes weight loss in mice

    Posted by .(JavaScript must be enabled to view this email address)
    Wednesday, March 31, 2004 11:15 am Email this article
    A Chinese herbal anti-obesity power known as Codonopsis Eupolyphaga causes weight loss in mice with diet-induced obesity according to a recent study.

    Animals given large doses of the powder for one month had reductions in total body fat, percent body fat, total cholesterol, triglycerides and blood sugar.

    However the powder had no effect on food intake, stool composition or measures of endurance.

    The authors hypothesized that the anti-obesity actions of the powder might be related to the metabolism of sugar and fat.

    The doses used were 0.2 to 1.1 grams per pound of body weight.

    I couldn’t find the term Codonopsis Eupolyphaga in any of my herb books.

    Paul Kneebone (.(JavaScript must be enabled to view this email address)) who runs The Codonopsis Website (http://www.kneebone.freeserve.co.uk) stated that it is not a species of Codonopsis, and suggested that it must be a mixture.

    According to another website (http://www.healthlink.com.au/nat_lib/htm-data/htm-herb/bhp853.htm (no longer on-line as of March 2004)) Eupolyphaga is salty, cold and slightly toxic.

    But what is it? Boiled and dried cockroach.

    Apparently it is used in Chinese Medicine.

    Let me know how it is, won’t you?


    Wang W; Zhao DZ; Sun BH. [Study on effects of Codonopsis eupolyphaga anti-obesity powder in mice with nutritive obesity]. Chung-Kuo Chung Hsi i Chieh Ho Tsa Chih, 1997 Dec, 17(12):739-41.

    Articles on the same subject can be found here:


    On Nov 08, 2004 at 3:50 pm DrJ wrote:

    . . . . .

    Though I have never heard of the formula, it is likely that Codonopsis Eupolyphaga is actually a formula name rather than a name of a single substance. Commonly, a chinese formula will be named for 1-2 key herbs in the preparation. Rarely are single herbs used or studied. This is likely a formula containing Dang Shen (codonopsis - a root and Qi tonic sometimes called "poor man's ginseng") and Zhi Chong - also called Di Bie Chong or Tu Bie Chong (cochroach). Since I am unfamiliar with the formula I do not know the other ingredients.

    Great website by the way. Very glad I found it.

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