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  • 540 mg of rubidium chloride for 3 weeks had antidepressant effect in 15 depressed people

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    Tuesday, May 24, 2016 5:10 pm Email this article

    Fifteen (15) hospitalized patients with depression were treated with 540 mg of rubidium chloride per day for three weeks according to a 1996 study.

    “Speed therapeutic efficacy has been shown, with lack of side effects,” the paper, written in Italian, notes.

    Rubidium causes stimulation of dopamine release which reduces depressive symptoms according to the paper.

    I do not have a copy of this paper, which is written in Italian, so I can only tell you what is in the abstract.

    Information on Rubidium Chloride from Wikipedia

    The Wikipedia entry for Rubidium chloride says

    “RbCl has been used as an antidepressant in Europe under the trade name Rubinorm in doses ranging from 180 to 720 mg.

    “Every 18 mg of RbCl is approximately equivalent to 1 Banana equivalent dose due to the large fraction (27.8%) of naturally occurring isotope Rubidium-87.

    “It increases dopamine and norepinephrine levels and has stimulating effects, hence it is useful for anergic and apathetic depressives.”


    Brundusino AO, and Cairoli S. [The pharmacological action of rubidium chloride in depression]. Minerva Psichiatr, 1996 Mar; 37(1): 45-49.

    Author’s Contact Info

    Farmacologia Medica II
    Universita degli Studi, Pavia
    [University in Pavia, Italy]

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