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High-protein diet associated with 4.3-fold greater risk of cancer death over 18 yrs in those 50-65
Monday, August 22, 2016 7:47 am Email this article
People 50- to 65-years old who consumed a high-protein diet, defined as consuming 20% or more of calories from protein, were 4.3 times more likely to die from cancer over the next 18 years than people who consumed a low-protein diet, defined as consuming less than 10% of calories from protein, according to a study from researchers at the University of Southern California in Los Angeles, California, USA.
“None of these associations was significantly affected by controlling for percent calories from total fat or for percent calories from total carbohydrates,” the paper notes.
“However, when the percent calories from animal protein was controlled for, the association between total protein and all-cause or cancer mortality was eliminated or significantly reduced, respectively, suggesting animal proteins are responsible for a significant portion of these relationships.”
Subjects: 6,381 adults ages 50 and over from the U.S.
The study included 6,381 adults ages 50 and over from NHANES III, a nationally representative, cross-sectional study in the U.S. who were followed for 18 years.
This article was originally published on May 2, 2014.
Levine ME, Suarez JA, Brandhorst S, Balasubramanian P, Cheng CW, Madia F, Fontana L, Mirisola MG, Guevara-Aguirre J, Wan J, Passarino G, Kennedy BK, Wei M, Cohen P, Crimmins EM, and Longo VD. Low Protein Intake Is Associated with a Major Reduction in IGF-1, Cancer, and Overall Mortality in the 65 and Younger but Not Older Population. Cell Metab, 2014 Mar 4; 19(3): 407-417.
Author’s Contact Info
Valter D. Longo
Davis School of Gerontology and Department of Biological Sciences
University of Southern California
Los Angeles, CA 90089-2520, USA
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