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  • Prolonged use of statins associated with a 29% increased risk of bladder cancer


    Posted by .(JavaScript must be enabled to view this email address)
    Wednesday, August 01, 2018 8:38 am Email this article

    Prolonged use of statins for more than 4 years was associated with a 29% increased risk of bladder cancer according to a recent analysis of data from 574 UK general practices from 1998-2008.

     

    Data

    Data from 574 UK general practices from 1998-2008

    “A series of nested case-control studies was conducted covering 574 UK general practices within the QResearch database,” the paper notes.

    “Cases were patients with primary cancers diagnosed between 1998 and 2008.

    “The associations between statin use and risk of ten site-specific cancers were estimated with conditional logistic regression adjusted for co-morbidities, smoking status, socio-economic status, and use of non-steroidal anti-inflammatory drugs, cyclo-oxygenase-2 inhibitors and aspirin.

    “88125 cases and 362254 matched controls were analysed.”

    Reference

    Vinogradova Y, Coupland C, and Hippisley-Cox J. Exposure to statins and risk of common cancers: a series of nested case-control studies. BMC Cancer, 2011; 11: 409.

    Author’s Contact Info

    Yana Vinogradova
    Division of Primary Care
    13th floor, Tower Building
    University Park
    Nottingham, NG2 7RD, UK.
    .(JavaScript must be enabled to view this email address)

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