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‘Virtually all trials of psychotropic agents are flawed’ says Peter Gotzsche, MD
Thursday, November 26, 2015 6:06 am Email this article
“Virtually all trials of psychotropic agents are flawed, not only because of the unblinding problem, but also because of their design,” writes Prof. Peter C. Gotzsche, MD in Chapter 3 titled Depression of his excellent book Deadly Psychiatry and Organised Denial.
“This was recognised decades ago, but drug trials and reviews have continued to pretend the problem doesn’t exist, likely because the psychiatrists choose to ignore everything that threatens the myths they have built up around their profession.
“There are many tricks.
“Some studies exclude patients who improve in the placebo lead-in period; some studies use active drugs in this period and exclude people who experience troublesome side effects; and some studies have both types of ‘cleansing,’ which was the case for one of the very few trials of fluoxetine in children that purported to have shown an effect.
“But even with this extremely biased design, the children fared no better on the drug than on placebo on self-rating scales or on ratings by their parents.
“The ‘effect’ was only seen on a secondary scale filled out by the psychiatrists who were paid by Lilly to run the trial!”
Other Quotes from This Book
Other quotes from Prof. Gotzsche’s book
Other quotes from Prof. Gotzsche’s book can be found here.
Other Comments from Prof. Gotzsche
Other Comments from Prof. Gotzsche found here
Other comments by Prof. Gotzsche (which includes other quotes from this book) can be found here.
A Must-Read Book
This is a must-read book for anyone interested in psychiatric drugs
For anyone interested in psychiatric drugs, this is a must-read book.
Anyone who thinks that psychiatric drugs are safe and effective must read this book.
Anyone who thinks that you can believe the published research about these drugs must read this book.
Anyone who thinks that you can believe what the American Psychiatric Association says about these drugs must read this book.
Anyone who thinks that you can believe what the US National Institutes of Mental Health says about these drugs must read this book.
Anyone who thinks that you can believe what the FDA says about the safety of these drugs must read this book.
My Mother Suffered Tragically From These Drugs
Larry’s mother suffered tragically from psychiatric drugs
My mother (Larry Hobbs’s mother) suffered tragically from psychiatric drugs, so this topic is of great interest to me.
About the Peter C. Gøtzsche, MD
Professor Peter C. Gøtzsche graduated as a Master of Science in biology and chemistry in 1974 and as a physician in 1984. He is a specialist in internal medicine; worked in the drug industry 1975-83, and at hospitals in Copenhagen 1984-95. With about 80 others, he helped start The Cochrane Collaboration in 1993 with the founder, Sir Iain Chalmers, and established The Nordic Cochrane Centre the same year. He became professor of Clinical Research Design and Analysis in 2010 at the University of Copenhagen.
Gøtzsche has published more than 70 papers in “the big five” (BMJ, Lancet, JAMA, Annals of Internal Medicine and New England Journal of Medicine) and his scientific works have been cited over 15,000 times.
Other articles about Prof. Peter Gotzsche, MD
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