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  • Fluoxetine (Prozac) caused 3-fold increased risk of suicide compared to placebo

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    Friday, February 05, 2016 1:00 am Email this article

    Fluoxetine (Prozac) and other serotonin reuptake inhibitors (SSRI’s) increase the risk of suicide. The Boston Globe wrote an article talking about this in 2000. The article noted that…

    “Three years before Prozac [fluoxetine] received approval by the US Food and Drug Administration in late 1987, the German BGA, that country’s FDA equivalent, had such serious reservations about Prozac’s safety that it refused to approve the antidepressant based on Lilly’s studies showing that previously nonsuicidal patients who took the drug had a fivefold [5-fold] higher rate of suicides and suicide attempts than those on older antidepressants, and a threefold [3-fold] higher rate than those taking placebos.”


    Garnett LR. Prozac revisited: As drug gets remade, concerns about suicides surface. Boston Globe, 2000 May 7; Posted on http://ahrp.org/prozac-revisited-concerns-about-suicides-surface-boston-globe/

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