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    180 to 720 mg of rubidium chloride had a significant antidepressant effect in two-thirds of patients


    Posted by .(JavaScript must be enabled to view this email address)
    Tuesday, May 24, 2016 5:39 pm Email this article

    Thirty-one female patients hospitalized for depression were given from 180 to 720 mg of rubidium chloride per day.

    “By week 2, at least two-thirds had improved significantly” the paper notes.

    Adverse Effects: Diarrhea, Increase Urine, Excitement

    Side effects included diarrhea, polyuria (producing abnormally large volumes of urine), and excitement, but were generally mild and rarely required interruption of the trial.

    Note:

    Reference

    Placidi G, Lenzi A, Lazzerini F, Dell’Osso L, Cassano GB, and Akiskal HS. Exploration of the clinical profile of rubidium chloride in depression: a systematic open trial. J Clin Psychopharmacol, 1988 Jun; 8(3): 184-188.

    Author’s Contact Info

    Institute of Clinical Psychiatry,
    University of Pisa, Italy

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