Niacin lowers C-reactive protein (CPR) by an average of 24%

Posted by .(JavaScript must be enabled to view this email address)
Thursday, March 05, 2020 6:20 am Email this article

Extended-release niacin (1500 to 2000 mg per day) lowers levels of C-reactive protein (CRP) by an average of 24% in people starting with higher levels of Lp(a)—starting levels of 92 mg/dL versus 54 mg/dL—according to a study from Russia.

Elevated levels of C-reative protein—above 2 mg/dL—are associated with an increased risk of heart and stroke as noted by the Mayo Clinic.

Note: I prefer immediate-release niacin to extended-release niacin. In the 1980’s there were reports of some liver problems with extended-release niacin, and earlier studies showing benefits of niacin used immediate-release niacin, not extended-release.

Reference

Artemeva NV, Safarova MS, Ezhov MV, Afanasieva OI, Dmitrieva OA, and Pokrovsky SN. Lowering of lipoprotein(a) level under niacin treatment is dependent on apolipoprotein(a) phenotype. Atheroscler Suppl, 2015 May; 18: 53-58.

Author’s Contact Info

N. V. Artemeva
Atherosclerosis Department
Institute of Clinical Cardiology
Federal State Institution
“Russian Cardiology Research and Production Center” of
Ministry of Health of the Russian Federation
15A, 3d Cherepkovskaya Street
Moscow 121552, Russia
.(JavaScript must be enabled to view this email address)

Other articles about niacin

Niacin lowers risk of heart attack or dying from a heart attack by an average of 25%

Niacin lowers risk of stroke by an average of 26%

Niacin raises HDL by an average of 20%

Niacin lowers LDL by an average of 16%

Niacin lowers triglycerides by an average of 20%

Niacin lowers Lp(a) by an average of 28%

Niacin lowers C-reactive protein by an average of 24%

Niacin use associated with a 25% reduction in heart attack or cardiac death

Niacin use associated with a 34% reduction in cardiovascular events

3 grams of niacin reduced stroke risk by 24% during 6.5 year follow-up

3 grams of niacin reduced heart attack risk by 26% during 6.5 year follow-up

3 grams of niacin reduced coronary revascularization risk by 67% during 6.5 year follow-up

3 grams of niacin reduced total mortality by 11% at a 15 year follow-up

Niacin may increase lifespan, Abram Hoffer, MD and Linus Pauling, PhD live to 92 and 93

Paradoxically the more Zetia (ezetimibe) lowered LDL, the greater the progression of atherosclerosis

Dose of extended-release niacin, 2000 mg in 75%, 1500 mg in 3%, 1000 mg in 12%, 500 mg in 10%

Niacin reduced total deaths by 86% compared to Zetia (ezetimibe) in statin users (1 vs 7 deaths)

Niacin reduced heart attacks by 67% versus Zetia (ezetimibe) in statin users (1 vs 3 heart attacks)

Niacin eliminated heart bypasses by 100% versus Zetia (ezetimibe) in statin users (0 vs 3 bypasses)

Niacin reduced cardiovascular deaths 80% versus Zetia (ezetimibe) in statin users (1 vs 5 deaths)

Articles on the same subject can be found here:

• C-reactive protein

• Cholesterol

• Cholesterol drugs

• Heart Disease

• Lp(a)

• Niacin (vitamin B3)