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Niacin lowers C-reactive protein (CPR) by an average of 24%
Sunday, May 13, 2018 6:20 am Email this article
Extended-release niacin (1500 to 2000 mg per day) lowers levels of C-reactive protein (CRP) by an average of 24% in people starting with higher levels of Lp(a)—starting levels of 92 mg/dL versus 54 mg/dL—according to a study from Russia.
Elevated levels of C-reative protein—above 2 mg/dL—are associated with an increased risk of heart and stroke as noted by the Mayo Clinic.
Note: I prefer immediate-release niacin to extended-release niacin. In the 1980’s there were reports of some liver problems with extended-release niacin, and earlier studies showing benefits of niacin used immediate-release niacin, not extended-release.
Artemeva NV, Safarova MS, Ezhov MV, Afanasieva OI, Dmitrieva OA, and Pokrovsky SN. Lowering of lipoprotein(a) level under niacin treatment is dependent on apolipoprotein(a) phenotype. Atheroscler Suppl, 2015 May; 18: 53-58.
Author’s Contact Info
N. V. Artemeva
Institute of Clinical Cardiology
Federal State Institution
“Russian Cardiology Research and Production Center” of
Ministry of Health of the Russian Federation
15A, 3d Cherepkovskaya Street
Moscow 121552, Russia
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