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Men with higher total cholesterol levels were 18-29% less likely to get Parkinson’s
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Sunday, September 16, 2018 7:25 am Email this article
Men not taking statins with higher total cholesterol levels — above 180 mg/dL — were 18-29% less likely to get Parkinson’s disease than those with lower cholesterol levels.
Men not taking statins with the middle one-third total cholesterol levels — above 180 mg/dL — were 18% less likely to get Parkinson’s during an average follow-up of 7.9 years compared to men with the one-third lowest total cholesterol levels.
Men not taking statins with the highest one-third total cholesterol levels were 29% less likely to get Parkinson’s compared to men with the one-third lowest total cholesterol levels.
(I have requested a copy of the paper to get exact cholesterol levels for each group. I will update this article when I do.)
Subjects: 261,638 people aged 40 to 79 not taking statins
This study looked at data from 261,638 people aged 40 to 79 who were not taking statins collected from the medical databases of Maccabi Health Services, the second largest health maintenance organization in Israel and who had their cholesterol levels measured from at least twice between 1999 to 2012.
A total of 764 people (3.3% of the total) who were 65 years and older were diagnosed with Parkinson’s during an average follow-up of 7.9 years.
Reference
Rozani V, Gurevich T, Giladi N, El-Ad B, Tsamir J, Hemo B, and Peretz C. Higher serum cholesterol and decreased Parkinson’s disease risk: A statin-free cohort study. Mov Disord, 2018 Aug 25; published online.
Author’s Contact Info
Dr. Nir Giladi
Neurological Institute
Tel Aviv Medical Center,
Sagol School of Neuroscience
Sackler Faculty of Medicine
Tel Aviv University
6 Weizmann Street
Tel Aviv 6423906, Israel
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