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Saccharin releases fat and increases thermogenesis, NutraSweet (aspartame) does the opposite
Wednesday, April 28, 2004 12:37 am Email this article
SACCHARIN, THE ARTIFICIAL SWEETENER, increases lipolysis (the release of fat from fat cells) in rats according to one study.
Animals fed 2.5 percent of their diet as sodium saccharin (added to their water) had twice the rate of lipolysis as those given less (either 1 percent or none).
SLIGHTLY LOWER BODY WEIGHT
The body weight of animals fed 1 percent or 2.5 percent saccharin was slightly lower than that of controls, however, the difference was not statistically significant.
Some researchers have suggested that simply increasing lipolysis, that is releasing more fat from fat cells, is not adequate to produce weight loss. In order to lose weight, you also need to burn the fat that is released.
5 PERCENT SACCHARIN CAUSES HUGE WEIGHT LOSS
Rats fed 5 percent saccharin weighed nearly 50 percent less than controls, however, this level of intake was considered unsafe.
NUTRASWEET REDUCES cAMP; MIGHT REDUCE THERMOGENESIS
Aspartame (NutraSweet) did not increase lipolysis, in fact at 2.5 percent of diet it decreased cAMP (the compound responsible for lipolysis and thermogenesis) in fat cells by 30 percent to 35 percent.
So aspartame may be counter-productive as far as thermogenesis for people trying to lose weight. However, a number of studies have found that people consuming aspartame weight less than those who do not, and those using the most, weighed the least.
SAFETY CONCERNS ABOUT NUTRASWEET
However, there are a number of safety concerns about aspartame. Personally, I don’t use it. However, I cannot necessarily say that the benefits of lower weight do not outweigh the potential risks.
SACCHARIN WAS DISCOVERED IN 1879
Saccharin was discovered in 1879 and is found in sugar substitutes like Sweet-N-Low and Sugar Twin.
SACCHARIN DOES NOT INCREASE BLADDER CANCER
Epidemiological studies (Chappel, 1992) have shown that saccharin does not increase the risk of bladder cancer in humans as once thought.
Dib K, Oget I, Wrisez F, Jamali AE, Aguie-Aguie G, Correze C, Lambert B. Effects of sodium saccharin diet on fat cell lipolysis: evidence for increased function of the adenylyl cyclase catalyst. International Journal of Obesity, 20:15-20, Jan 1996.
Chappel CI. A review and biological risk assessment of sodium saccharin. Regulatory Toxicology and Pharmacology, 15(3):253-70, Jun 1992.
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