High-intensity statin therapy increases risk of acute kidney injury by 16%

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Friday, April 05, 2019 11:15 am Email this article

High-intensity statin therapy was found to increase the risk of hospitalization for acute kidney injury by 16% compared to non-users during a median follow-up of 4.6 years according to a new study.

High-intensity statin therapy was defined as:

• Rosuvastatin 10 mg or more
• Atorvastatin 20 mg or more
• Simvastatin 80 mg or more

Reference

Tonelli M, Lloyd AM, Bello AK, James MT, Klarenbach SW, McAlister FA, Manns BJ, Tsuyuki RT, and Hemmelgarn BR. Statin use and the risk of acute kidney injury in older adults. BMC Nephrol, 2019 Mar 25; 20(1): 103.

The paper is posted here:
https://bmcnephrol.biomedcentral.com/articles/10.1186/s12882-019-1280-7

Author’s Contact Info

Marcello Tonelli
Department of Medicine
University of Calgary
7th Floor, TRW Building
3280 Hospital Drive NW
Calgary, Alberta T2N 4Z6, Canada
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Articles on the same subject can be found here:

• Kidney Injury, Acute

• Statins