QUICKLINKS AND VIEW OPITONS
Acomplia (rimonabant) causes average weight loss of 15.2 lbs with 20 mg, 6.7 lbs with 5 mg
Monday, March 12, 2007 4:15 am Email this article
Patients given 20 mg of Acomplia (rimonobant) per day lost an average 15.2 pounds in the Rimonobant In Obesity--Lipids study (RIO-Lipids) according to a review paper about the drug. This compares to 6.7 pounds for those given 5 mg, and 3.3 pounds for those given a placebo. 10% Weight Loss
Weight loss of 10% or more: 33% in 20 mg group, 7% in placebo group
Roughly one-third of patients given 20 mg per day (32.6 percent) lost at least 10 percent of their body weight compared to 7.2 percent in the placebo group.
5% Weight Loss
Weight loss of 5% or more: 58% in 20 mg group, 20% in placebo group
Roughly two-thirds of patients given 20 mg per day (58.4 percent) lost at least 5 percent of their body weight compared to 19.5 percent in the placebo group.
Subjects: 1033 overweight and obese adults
The study involved 1033 men and women over the age of 18 with a body mass index (BMI) of 27-40 and lasted for one year.
Bifulco M, Grimaldi C, Gazzerro P, Pisanti S, Santoro A. Rimonabant: Just an anti-obesity drug? Current evidence on its pleiotropic effects. Mol Pharmacol. 2007 Feb 27.
Priti N. Patel, PharmD, BCPS
Assistant Clinical Professor
College of Pharmacy and Allied Health Professions
St. John’s University
St. Albert Hall, Room 114
8000 Utopia Parkway
Queens, NY 11439
Articles on the same subject can be found here:
Please feel free to share your comments about this article.
© Copyright 2003-2017 - Larry Hobbs - All Rights Reserved.