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    Arginine-fed rats gained 40-70% less weight


    Posted by .(JavaScript must be enabled to view this email address)
    Friday, February 27, 2009 2:33 pm Email this article
    Growing rats fed arginine gained 40-70% less weight according to a new study from the Feb 2009 issue of the Journal of Nutrition.

    Here is the fifth video highlight from this paper.

    In this video, I compare the weight gain in each group.

    Briefly, here is how the study was done.

    Rats that were about 5 months old were put on either a low-fat diet (10% of calories as fat) or a high fat diet (40% of calories as fat) and given either arginine or alanine (another amino acid to provide the same amount of nitrogen) in their drinking water for 3 months.

    After 3 months, they compared body weight, body fat, and muscle.

    For rats fed a low-fat diet—10% of calories as fat—, those given arginine, only gained one-third as much weight as those in the control group.

    To put it another way, rats in the control group fed a low-fat diet gained 3 times as much weight as those given arginine.

    For rats fed a low-fat diet—40% of calories as fat—, those given arginine, only gained two-thirds as much weight as those in the control group, or about one-third less.

    To be more exact, about 40% less.

    To put this another way, rats in the control group on a high-fat diet gained two-thirds (67%) more than those given arginine.

    It is also interesting to compare the control rats in the low-fat group to the arginine-fed rats in the high-fat group.

    Rats in the high-fat group given arginine even gained less weight—about one-sixth less weight—than the control rats in the low-fat group.

    This is the fifth video highlight from this paper.

    I will post more video highlights from this paper.

    REFERENCE

    Jobgen W, Meininger C, Jobgen S, Li P, Lee MJ, Smith S, Spencer T, Fried S, Wu G. Dietary l-arginine supplementation reduces white fat gain and enhances skeletal muscle and brown fat masses in diet-induced obese rats. J Nutr. 2009 Feb, 139(2):230-37.

    AUTHOR’S CONTACT INFORMATION

    Guoyao Wu
    Department of Animal Science
    Faculty of Nutrition
    Texas A&M University
    College Station, TX 77843, USA
    .(JavaScript must be enabled to view this email address)

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