Fructose-induced metabolic syndrome is associated with changes in the kidney

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Tuesday, September 05, 2006 4:08 am Email this article
I reported the other day that fructose increase uric acid which can cause metabolic syndrome. A new study in rats also found that metabolic syndrome induced by a high fructose intake is also associated with changes in the kidneys. Kidney Changes

Specific changes

Specific changes seen in rats fed a diet containing 60 percent fructose included:

• renal hypertrophy—enlargement of the kidneys
• arteriolopathy—damage to minute arteries
• glomerular hypertension
• renal cortical vasoconstriction

To me, the importance of the story is not specifically what happens, but rather that consuming too much fructose is not healthy.

REFERENCE

Sanchez-Lozada LG, Tapia E, Jimenez A, Bautista P, Cristobal M, Nepomuceno T, Soto V, Avila-Casado C, Nakagawa T, Johnson R, Herrera-Acosta J, Franco M. Fructose-induced metabolic syndrome is associated with glomerular hypertension and renal microvascular damage in rats. Am J Physiol Renal Physiol. 2006 Aug 29.

AUTHOR’S CORRESPONDENCE

Nephrology
INC Ignacio Chavez
Mexico City, D.F., Mexico

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• Fructose