Grehlin nocturnal rise blunted in obese

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Monday, July 05, 2004 1:40 pm Email this article
The nighttime rise in ghrehlin is blunted in people who are obese according to a new study from the University of California, Los Angeles.

The implications of this finding are not clear.

Ghrehlin is a hormone, produced primarily by the stomach, that increases food intake and is thought to play a role in the long-term regulation of body weight.

REFERENCE

Yildiz B, Suchard M, Wong M, Mccann S, Licinio J. Alterations in the dynamics of circulating ghrelin, adiponectin, and leptin in human obesity. Proc Natl Acad Sci U S A. 2004 Jul 1.

AUTHOR CORRESPONDENCE

B Yildiz
Center for Pharmacogenomics and Clinical Pharmacology
Neuropsychiatric Institute
Division of Endocrinology, Diabetes, and Hypertension
Department of Medicine, and
Departments of Biomathematics and Psychiatry and Biobehavioral Sciences
David Geffen School of Medicine
University of California, Los Angeles, CA 90095-1761

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