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Meridia (sibutramine) causes average weight loss of 9.8 lbs after one year
Monday, April 25, 2005 9:22 am Email this article
Meridia (sibutramine) causes an average weight loss of 9.8 pounds more than placebo after one year according to a analysis by the RAND Corporation. Meridia weight loss after four to six months: 7.5 to 13.2 lbs
The average weight loss in twelve studies lasting four to six months varied from 7.5 pounds to 13.2 pounds.
Meridia weight loss after one year: 9.8 lbs
The average weight loss in five studies lasting ten months to one year varied was 9.8 pounds.
Meridia increased pulse 4 beats per minute
Meridia (sibutramine) increased heart rate by an average of 4 beats per minute.
Serious adverse effects: 1.5 per 1000 patients
Serious adverse effects could occur in as many as 1.5 out of every 1,000 patients taking Meridia according to the paper.
Li Z, Maglione M, Tu W, Mojica W, Arterburn D, Shugarman L, Hilton L, Suttorp M, Solomon V, Shekelle P, Morton S. Meta-analysis: pharmacologic treatment of obesity. Ann Intern Med. 2005 Apr 5, 142(7):532-46.
AUTHOR’S CONTACT INFORMATION
Southern California Evidence-Based Practice Center
RAND Health Division
1776 Main Street
Santa Monica, CA 90401-3208
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