fatnews.com Fatnews Bitchute Channel Link Home page  >  Article | Previous article | Next article



  • Categories of Articles
  • Summary View
  • Headline View
  • Archive of Quotes
  • Contact Us
  • Metformin plus Glyburide causes 20% weight loss in diabetics

    Posted by .(JavaScript must be enabled to view this email address)
    Friday, November 21, 2003 5:50 am Email this article
    SOME STUDIES HAVE SHOWN that type II diabetics lose small amounts of weight using the drug metformin (Glucophage). However combining metformin with glyburide (Micronase) worked significantly better than either one alone according to a recent study.

    For two months type II diabetics who were previously on insulin were given either metformin (850 mg three times per day) or glyburide (5 mg three times per day) or a combination of both drugs (500 mg metformin plus 2.5 mg glyburide three times per day). Patients also ate a reduced calorie diet of 1200 to 1800 calories per day. Those taking either drug alone did not lose a significant amount of weight, but those taking both drugs lost 20% of their body weight. There was also a reduction in cholesterol and triglycerides by 29% and 60%, respectively.

    There is no evidence that this combination would work in non-diabetics and could potentially cause severe and even fatal hypoglycemia. Metformin works by improving insulin sensitivity which reduces the body’s need for insulin. While glyburide works by initially increasing insulin production followed by a decrease in glucose production by the liver and an increase in insulin sensitivity.


    Gentile S, Turco S. An alternative treatment with glibenclamide-metformin in obese type 2 diabetic patients on abusive. International Journal of Obesity, May 1996, 20(Supplement 4):152 (abstract 20-503-FP3).

    Articles on the same subject can be found here:


    Please feel free to share your comments about this article.




    Please enter the word you see in the image below:

    Remember my personal information

    Notify me of follow-up comments?

    © Copyright 2003-2021 - Larry Hobbs - All Rights Reserved.