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  • Patients lost 21 pounds or 9.5% of body weight in six weeks on 800 calorie liquid meal replacement

    Posted by .(JavaScript must be enabled to view this email address)
    Monday, August 23, 2010 1:56 pm Email this article
    Patients lost an average of 21.2 pounds or 9.5 percent of body weight in six weeks when give a 800 calorie per day liquid meal replacement, which consisted of HMR 800 (Health Management Resources, Boston, Massachusetts, USA).

    Information about the HMR 800 meal replacement shakes can be found here.

    Note: A couple of weight loss doctors have told me that HMR makes the best meal replacement shakes of any they have tried.

    Note: I have no financial ties to HMR or this product. Subjects

    Subjects: 774 adults

    The study involved a total of 784 men and women who were recruited at 35 sites in the United States and Europe.


    Weight Regain After One Year

    Weight Regain after one year: 3.7 lbs

    Patients given a placebo had regained 3.7 lbs after one year.

    Patients given 0.5 mg of the drug Taranabant lost an additional 0.2 lbs—almost nothing.

    Patients given 1.0 mg of the drug Taranabant lost an additional 1.4 lbs.

    Patients given 2.0 mg of the drug Taranabant lost an additional 2.6 lbs.

    Because of psychiatric problems with Taranabant, it seems unlikely that this drug will ever be approved for sale in the US, therefore, I wanted to focus this article on the initial weight loss with the 800 calorie meal replacement shakes.


    Wadden T, Fujioka K, Toubro S, Gantz I, E Erondu N, Chen M, Suryawanshi S, Carofano W, Johnson-Levonas AO, R Shapiro D, Kaufman K, Heymsfield S, Amatruda J. A randomized trial of lifestyle modification and taranabant for maintaining weight loss achieved with a low-calorie diet. Obesity (Silver Spring). 2010 Apr 8, Epub ahead of print.


    Thomas A. Wadden
    University of Pennsylvania School of Medicine
    Department of Psychiatry
    Center for Weight and Eating Disorders
    Philadelphia, Pennsylvania, USA
    .(JavaScript must be enabled to view this email address)



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