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Taranabant side effects : Depression in 6-7% of patients taking 2-6 mg
Monday, March 10, 2008 2:33 pm Email this article
In a dosing study of the diet drug taranabant, depression was reported by
- 2.9 percent of those given a placebo
- 4.7 percent of patient given 0.5 mg
- 5.5 percent of those given 2 mg
- 6.7 percent of those give 4 mg
- 5.6 percent of those given 6 mg.
Subjects : 533 people
The study involved 533 patients.
Addy C, Wright H, Laere KV, Gantz I, Erondu N, Musser BJ, Lu K, Yuan J, Sanabria-Bohórquez SM, Stoch A, Stevens C, Fong TM, Lepeleire ID, Cilissen C, Cote J, Rosko K, III ING, Nguyen AM, Gumbiner B, Rothenberg P, Hoon JD, Bormans G, Depré M, Eng W-S, Ravussin E, Klein S, Blundell J, Herman GA, Burns HD, Hargreaves RJ, Wagner J, Gottesdiener K, Amatruda JM, Heymsfield SB. The acyclic cb1r inverse agonist taranabant mediates weight loss by increasing energy expenditure and decreasing caloric intake. Cell Metab. 2008 Jan, 7(1):1-2.
AUTHOR’S CONTACT INFORMATION
Steven B. Heymsﬁeld, M.D.
Merck Research Laboratories
Rahway, NJ 07065, USA
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