fatnews.com

Discussion Forums
NEW!

Discussion Forums

Recent Forum Topics
NEW!

Recent Forum Topics
We welcome your comments, experience, expertise and insight on various topics about weight loss in these discussion forums.

STORE

The Store

SEARCH THIS SITE


Advanced Search

SEARCH THE WEB

Google

CONTACT US

  • Contact Us
  • Submit your suggestions to improve this site
  • Submit an article you would like reviewed
  • Suggest a drug, nutrient or diet you would like reviewed
  • TABLES

    BMI Table for adults
    BMI Table defining childhood obesity
    Glycemic Index Tables

    MEMBERS

    Login
    Register

    MAILING LIST

    CATEGORIES

    (Tip: To find articles about a particular subject, either search for a particular word, click "Category View" above, or select the category you are interested in from the list below.)
    5-HTP (5-Hydroxytryptophan)
    9 things I've learned about doctors
    Abilify (aripiprazole)
    Acarbose (Precose)
    Accountability
    ACE Inhibitor
    Acetyl-L-Carnitine
    Acomplia (rimonabant)
    Actonel (risedronate)
    Actos (pioglitazone)
    Adherence (compliance) to treatment
    Adiponectin
    Aging
    AIDS
    Air Conditioning
    Alcohol
    Alcoholism
    Alii (orlistat) - (also see Xenical)
    All-you-can-eat
    Allergies, Food and Brain
    Almonds
    Alpha Lipoic Acid
    Aluminum
    Alzhemier's Disease
    Amantadine (Symmetrel)
    Ambien (zolpidem)
    Amino Acids
    Amitriptyline (See Elavil)
    Amphetamines
    Amylase inhibitors (See Starch Blockers)
    Amyotrophic Lateral Sclerosis (ALS)
    Anafranil (clomipramine)
    Angina (chest pain)
    Animal-based diet
    Antibiotics
    Antidepressants
    Antihistamines
    Antipsychotic drugs
    Anxiety
    Arginine
    Arthritis
    Articles by others
    Artificial sweetners (general)
    Aspartic Acid
    Aspirin
    Asthma
    Attention Deficit Hyperactive Disorder -- ADHD
    Autism
    Avandia (rosiglitazone)
    Axokine
    Azithromycin
    Bariatric Surgery (See Weight Loss Surgery)
    Behavioral Therapy, Cognitive
    Belviq (lorcaserin hydrochloride)
    Benefits of weight loss
    Benzodiazepines
    Beta Blockers
    Binge Eating
    Bioidentical hormones
    Birth Control Pills
    Bisphosphonates (osteoporosis drugs)
    Blacks
    Blood Donation
    Blood Pressure
    Blood Pressure Drugs
    Blood Pressure Drugs INCREASED Death in Older women
    Blood sugar
    BMI not perfect
    BMI Table
    BMI, Healthiest (Healthiest BMI)
    Body Composition
    Bone Fractures
    Bone mass
    Book - Blue Zones
    Book - Cholesterol Myths (by Uffe Ravnskov, MD, PhD)
    Book - Deadly Medicines and Organised Crime (by Prof. Peter Gøtzsche, MD)
    Book - Deadly Psychiatry and Organised Denial (by Prof. Peter Gøtzsche, MD)
    Book - Good Calories, Bad Calories (by Gary Taubes)
    Book - Malignant Medical Myths
    Book - Our Daily Meds
    Book - The Black Swan
    Book - The Plant Paradox (by Steven Gundry, MD)
    Book - Why We Get Fat (by Gary Taubes)
    Book: The Three Best Ways to Lose Weight
    Brain Allergies (See Allergies, Food and Brain)
    Breakfast
    Breast-feeding
    Broda Barnes, MD, PhD (thyroid expert)
    Bromocriptine (Ergoset)
    Bulimia
    Bupropion (See Wellbutrin)
    Byetta (exenatide)
    C-reactive protein
    Caffeine
    Calcium
    Calcium Channel Blockers
    Calorie content of food
    Calorie Density of Food
    Calorie Intake
    Calorie intake, Underreporting
    Calorie Restriction
    Cancer
    Cancer screening (Does it do any good?)
    Cancer treatments
    Cancer, Bladder
    Cancer, Bowel
    Cancer, Brain
    Cancer, Breast
    Cancer, Cervical
    Cancer, Colorectal
    Cancer, Endometrial
    Cancer, Gallbadder
    Cancer, Hodgkin's Lymphoma
    Cancer, Kidney
    Cancer, Leukemia
    Cancer, Liver
    Cancer, Lung
    Cancer, Multiple Myeloma
    Cancer, Non-Hodgkin's Lymphoma
    Cancer, Oesophageal
    Cancer, Oesophageal (adenocarcinoma)
    Cancer, others
    Cancer, Ovarian
    Cancer, Pancreatic
    Cancer, Prostate
    Cancer, Stomach (gastric cardia)
    Cannabis (marijuana)
    Caralluma fimbriata
    Carbohydrates
    Carnitine, L- (L-carnitine)
    Carpal tunnel syndrome
    Celexa (citalorpam)
    Cell Phones
    Cereal
    Chelation Therapy, EDTA
    Chemtrails
    Chewing
    Chickenpox
    Childhood Illnesses
    Childhood neglect and abuse
    Childhood Obesity
    Chitosan
    Chocolate (cocoa)
    Cholesterol
    Cholesterol drugs
    Cholesterol Hypothesis Skeptics
    Cholesterol Myths
    Cholesterol, HDL
    Cholesterol, LDL
    Chromium
    Chronic Fatigue
    Citrus aurantium
    CLA (Conjugated Linoleic Acid)
    Clozaril (clozapine)
    Cobalt
    Cochrane Collaboration
    Codonopsis Eupolyphaga
    Coffee
    Coffee, Decaffeinated
    Cognitive function
    Commercial Weight Loss Programs
    Computer Use
    Conflicts of Interest
    Congestive Heart Failure
    Constipation
    Contrave (Wellbutrin (bupropion) plus naltrexone)
    Copper
    CoQ10 (Coenzyme Q10, ubiquinol, ubiquinone)
    Coronavirus COVID-19
    Cortisol (stress hormone)
    Cost of food
    Costs associated with obesity
    Cravings
    Cymbalta (duloxetine)
    Daniel Amen, MD
    Death, Risk of
    Deaths from obesity
    Definitions
    Dementia (see Alzheimer's also)
    Dental Amalgams (mercury fillings)
    Depo-Provera (depot-medroxyprogesterone acetate)
    Depression
    Desire to Lose Weight
    DHEA
    Diabetes
    Diabetes drugs
    Diagnosed Overweight by a Doctor
    Dialysis
    Diet drug use
    Diet Pills (General Info)
    Diet soda
    Dietary Counseling
    Diethylpropion (Tenuate)
    Dieting (General)
    Dieting, Intermittent
    Dinitrophenol
    Disability
    Discrimination against obesity
    Diuretics
    Diverticulitis
    Doctor - Abram Hoffer, MD, PhD
    Doctor - Boyd Haley, PhD
    Doctor - Dr. Kailash Chand
    Doctor - H. Gilbert Welch, MD (author of Overdiagnosed and Less Medicine, More Health)
    Doctor - Irving Kirsch, PhD
    Doctor - Jason Fung, MD
    Doctor - Joel Kauffman, PhD (author of Malignant Medical Myths)
    Doctor - John Abramson, MD (author of Overdosed America)
    Doctor - Jonathan Wright, MD (pioneer in natural medicine)
    Doctor - Kimber Stanhope, PhD
    Doctor - Malcolm Kendrick, MD author of "The Great Cholesterol Con"
    Doctor - Marcia Angell, MD
    Doctor - Mary Enig, PhD
    Doctor - Michel de Lorgeril, MD
    Doctor - Peter Gøtzsche, MD
    Doctor - Robert Lustig, MD
    Doctor - Steven Gundry, MD
    Doctor - Suzanne Humphries, MD
    Doctor - Timothy Noakes
    Doctor - Uffe Ravnskov, MD PhD
    Doctor - William Wilson, MD
    Doctor trends
    Doctors are blind to drug-induced side effects
    Don't fall for this
    Dopamine agonists
    Drug company lies
    Drug Company Money
    Drug Company Salesman
    Drug Company Tactics
    Drug-induced Side Effects
    Dry Skin
    Duodenal Switch (weight loss surgery)
    Eating time of day
    Economic Issues and Obesity
    Education
    Eggs
    Elavil (amitriptyline)
    Elderly
    Elderly, risk of obesity
    Electrolyte abnormalities (magnesium, potassium, sodium, calcium, phosphate)
    Empatic (Zonegran plus Wellbutrin)
    Environmental chemicals
    Ephedrine/Ephedra
    Epigenetics
    Erectile Dysfunction
    Escitalopram (Lexapro)
    Estrogen replacement therapy
    Evening Primrose Oil
    Every Other Day Modified Fast
    Excalia
    Exercise
    Exhaustion
    Fast Food
    Fasting, Intermittent
    Fat Cells
    Fat Intake (Dietary Fat)
    Fat loss
    Fat Oxidation
    Fat Replacers
    Fat, Body (Body Fat)
    Fat, Dietary
    FDA (U.S. Food and Drug Administration)
    Fen-Phen
    Fertility (see Pregnancy)
    Fiber (Dietary Fiber)
    Fiber supplements
    Fidgeting
    Fish
    Fish Oil (omega-3 fatty acids)
    Flaxseed
    Food Allergies (See Allergies, Food and Brain)
    Food Cues
    Food Diary
    Food Intake statistics
    Food preferences associated with obesity
    Food Pyramid
    Food Safety
    Food's effect on appetite
    Foods associated with higher and lower body weight
    Foods Associated with Weight Gain
    Forskolin (from the plant Coleus forskohlii)
    Fosamax (alendronate)
    Fructose
    Fruit
    Fucoxanthin
    GABA
    Gallbadder Disease
    Gallstones
    Garlic
    Gastro-esophageal reflux disease
    General Health Checks
    Genes and genetics
    Geodon (ziprasidone)
    Ghrelin
    Ginger
    Ginseng
    GLA (Gamma Linolenic Acid)
    GLA - Gamma Linolenic Acid
    Glucomannan (konjac root)
    Glucophage (metformin)
    Glutamine (amino acid)
    Glycemic Index
    Glycemic Index Tables
    Glycomacropeptide
    GMO foods (genetically modified organisms)
    Grains
    Grapefruit
    Green coffee bean extract
    Green Tea
    Group Therapy
    Growth Hormone
    Guar gum
    Gut Bacteria
    Gwen Olsen
    Habits associated with obesity
    Habits of being lean
    Hair Loss (caused by weight loss)
    Haldol (haloperidol)
    Hawaiian Diet
    HCG (human chorionic gonadotropin)
    Headaches
    Health Insurance
    Health Risks of obesity
    Heart Attack (myocardial infarction)
    Heart Disease
    Heart Disease, Coronary - Skeptics of the Cholesterol Hypothesis
    Heavy metal toxicity
    Herbal formula, Number Ten
    Herbal formula, PM-F2-OB
    Hibiscus tea
    High Carbohydrate Diet
    High-Fructose Corn Syrup
    High-Protein / Low-Carb Diets
    Histamine levels
    History
    Holiday Weight Gain
    Homocysteine
    Hoodia
    Hop extract, isomerized
    Hunger
    Hydralazine
    Hydrogenated vegetable oil (partially hydrogenated oil)
    Hydroxychloroquine
    Hydroxycitrate (HCA)
    Hypoglycemia
    Hypothyroidism, including Type 2 Hypothyroidism
    IGF-1 (insulin-like growth factor-1)
    Income level
    Infections
    Infertility
    Influenza (Flu)
    Injuries
    Insulin
    Insulin sensitivity
    Interview with Patients
    Interview with Stephen Gullo, PhD
    Interviews
    Interviews with Doctors
    Iodine
    Jenny Craig Weight Loss Program
    Joan Mathews Larson, PhD
    John Ioannidis
    Just for Fun
    Kidney Disease
    Kidney Injury, Acute
    Kidney Stones
    Kidney stones
    Konjac root (See glucomannan)
    Krill Oil
    Lap Band Surgery
    Lead (heavy metal toxicity)
    Lean, things associated with being
    Legumes
    Leptin
    Lesbians
    Leucine (amino acid)
    Life Expectancy
    Lipolysis (release of fat from fat cells)
    Liposuction
    Lipozene (see glucomannan)
    Liquid Calories
    Liraglutide
    Longevity
    Lorcaserin (also see Belviq (lorcaserin hydrochloride))
    Low Calorie Diet
    Low Carbohydrate Diets
    Low Fat Diets
    Low Stomach Acid
    Lp(a)
    Ludiomil (maprotiline)
    Luvox (fluvoxamine)
    Magnesium
    Maitake mushroom
    Mammography
    Marijuana (see Cannabis)
    Mark Starr, MD
    Married or Single
    Meal Frequency
    Meal Replacement Shakes
    Measles
    Measurments of obesity
    Meat, Red
    Mediterranean Diet
    Medium chain triglycerides (MCT's)
    Men, studies about
    Menopause
    Menstruation
    Mercury
    Mercury fillings (Dental amalgams)
    Meridia (sibutramine)
    Metabolic syndrome (also see Insulin Sensitivity)
    Metabolism
    Mifeprex (mifepristone)
    Milk and Dairy
    Mineral aspartates
    Mirapex (pramipexole)
    Mirtazapine (antidepressant Remeron)
    Moban (molindone)
    Monounsaturated fat (Olive Oil and Canola Oil)
    Mortality associated with obesity
    Motivational techniques for losing weight
    Movies
    MSG (monosodium glutamate)
    Multiple Myeloma (See Cancer, Multiple Myeloma)
    Mumps
    Myths, Medical Myths
    N-Acetyl-Cysteine (NAC)
    Naltrexone
    Nasal Blockage
    Nassim Taleb
    Natural Treatments
    Nestatin-1
    Neurontin (gabapentin)
    Niacin (vitamin B3)
    Nicotine
    Night Eating Syndrome
    Night workers/shift workers
    No Dinner Diet
    Nonalcoholic fatty liver disease
    Nortriptyline (See Pamelor)
    Nutrasweet (aspartame)
    Nuts (also see Almonds)
    Obesity Forecasts
    Obesity Guidelines, NIH
    Obesity statistics
    Obesity Statistics, US States
    Obesity, Causes of
    Obesity, Factors associated with
    Oleoyl-estrone
    Olestra
    Olive Oil
    Omega-3 Fatty Acids (fish oil)
    Omega-6 Fatty Acids
    Onions
    Oolong Tea
    Opinion
    Orthomolecular Medicine
    Osteoporosis drugs (Bisphosphonates)
    Over-treatment
    Paleo Diet
    Pamelor (nortriptyline)
    Parent's influence on obesity
    Parkinson's Disease
    Paroxetine (antidepressant Paxil)
    PCSK9 inhibitors (cholesterol-lowering drugs)
    Pedometer
    Periactin (cyproheptadine)
    Periodontal Gum Disease
    Personal stories about weigh loss
    Phen-Pro (Phentermine-Prozac or other SSRIs)
    Phendimetrazine (Bontril)
    Phentermine
    Phenylephrine
    Phosphodiesterase type-5 inhibitors, sildenafil (Viagra), tadalafil (Cialis), vardenafil (Levitra)
    Plastic's effect on body weight
    Plate Size
    Pokeweed extract
    Polar Weight Management Program
    Polio Vaccine (Salk Vaccine)
    Polycystic Ovarian Syndrome
    Polyunsaturated Fat
    Port, Sidney (UCLA statistician)
    Portion size, effect on calore intake
    Post-traumatic stress disorder
    Postnatal weight gain (immediately after birth)
    Postpartum depression
    Potassium
    Pramlintide (see Symlin)
    Predicted Weight Loss
    Pregnancy
    Pregnant women, effects on offspring
    Prejudice against obesity
    Prevalence of Obesity
    Prices for drugs
    Prolixin (fluphenazine)
    Prostate, Enlarged
    Protamine
    Protein (general)
    Protein from meat
    Protein from nuts & seeds
    Protein from plants
    Protein Leverage Theory
    Protein Source
    Protein supplement
    Protein, High, Diet
    Protein, Low, Diet
    Protein, Soy
    Proton pump inhibitors
    Proton Pump Inhibitors (PPI's)
    Prozac (fluoxetine)
    PSA Test (Prostate Specific Antigen)
    Psychiatric Drugs
    Pu-erh Tea (Chinese Black Tea)
    Pursuing Weight Control
    Pyruvate
    Qsymia (phentermine and topiramate) (formerly Qnexa)
    Quality of Life
    Quercetin
    Radiation (background ionizing radiation)
    Rate of Eating
    Raw food diet
    Red Yeast Rice
    Remdesivir (anti-viral medication)
    Resistant Starch
    Resveratrol
    Rhodiola rosea (Golden root or Arctic root)
    Rice
    Richard Moore, MD, PhD
    Risperdal (risperidone)
    Ritalin (methylphenidate)
    Robert Skversky, MD
    Robert Whitaker (author & journalist)
    Rubidium
    Saccharin (artificial sweetner)
    Saturated Fat
    Sauna
    Scams
    Schizophrenia
    Seizures
    Self-help weight loss
    Self-reported height and weight
    Self-reported intake
    Serentil (mesoridazine)
    Serlect (sertindole)
    Seroquel (quetiapine)
    Serotonin Syndrome
    Serzone (nefazodone)
    Sex and Sexual Activity
    Sexual abuse
    Shift Workers
    Sick Days
    Simmondsin (jojoba plant seed extract)
    Skinny on Obesity video series
    Sleep
    Sleeping pills
    Smoking's effect on weight
    Snacks
    Snoring
    Social Influence
    Sodium Intake
    Soft drinks (Coke, Pepsi, etc.)
    South Beach Diet
    Splenda (sucralose)
    Spouses
    SSRI's
    Starch Blockers (Amylase inhibitors)
    Statin Nation (documentary)
    Statins
    Stearic Acid (in beef and chocolate)
    Stents (coronary artery stents)
    Strattera (atomoxetine)
    Strength Training
    Stress
    Stroke, hemorrhagic
    Stroke, ischemic
    Sugar Addiction
    Sugar intake
    Suicide
    Sumatriptan
    Sun Bathing, Benefits of
    Surmontil (trimipramine)
    Symlin (pramlintide)
    Symlin (pramlintide)
    Sympathetic Nervous Activity (SNS)
    Taranabant
    Tart Cherry Juice
    Taste
    Taubes, Gary
    Taxes and Obesity
    Tea
    Television Watching
    Temperature, House
    Tenuate (See diethylpropion)
    Termite fumigation (with sulfuryl fluoride)
    Tesofensine
    Testosterone
    Thermogenesis
    Thermography
    Thimerosal (mercury-containing preservative)
    Thorazine (chlorpromazine)
    Thyroid Function
    Thyroid supplement
    Thyroid, Desiccated
    Timeline related to obesity discoveries
    Tofranil (imipramine)
    Tofu (soybean curd)
    Tonsils
    Too much medicine
    Topamax (topiramate)
    TOPS (Take Off Pounds Sensibly)
    Trans Fats
    Trazedone (antidepressant)
    Tricyclic antidepressants
    Triglyceride levels
    Tryptophan
    Underreporting weight
    Urinary incontinence
    Vaccines
    Vegetable-based Diet
    Vegetables
    Vegetables, Raw
    Vegetarians
    Venlafaxine (antidepressant Effexor)
    Ventricular arrhythmias
    Vertical Banded Gastroplasty
    Very-Low-Calorie Diets
    Vibration, Whole Body
    Vinegar
    Virus and Bacteria associated with obesity
    Virus, obesity (adenovirus-36)
    Visual Cues
    Vitamin C
    Vitamin D
    Vitamins
    Waist measurement
    Waist-to-Hip Ratio
    Wansink, Brian (studies done by)
    Water
    Weighing, Self
    Weight cycling (gaining and losing)
    Weight gain
    Weight Lifting
    Weight Loss Expectations
    Weight Loss Programs
    Weight Loss Strategies
    Weight Loss Success (what successful weight losers do)
    Weight Loss Supplements
    Weight Loss Supplements, Adulterated
    Weight loss surgery
    Weight Loss Surgery - Laparoscopic Sleeve Gastrectomy
    Weight Loss, Benefits of
    Weight loss, Rate of
    Weight loss, risks of
    Weight Maintenance
    Weight monitoring
    Weight Perception
    Weight Watchers
    Weight-gaining drugs
    Wellbutrin (bupropion)
    Wine, Red
    Women, studies about
    Work, Lost Days
    Xenical (orlistat)
    YouTube videos
    Zerona laser
    Zetia (ezetimibe)
    Zinc
    Zocor (simvastatin)
    Zoloft (sertraline)
    Zonegran (zonisamide)
    Zyprexa (olanzapine)

    ARCHIVES

    July, 2020
    June, 2020
    May, 2020
    April, 2020
    March, 2020
    February, 2020
    January, 2020
    December, 2019
    November, 2019
    October, 2019
    September, 2019
    August, 2019

    ARCHIVE SUMMARY

    View by Date
    View by Category

    RSS / XML


    RSS 1.0
    RSS 2.0
    RSS Atom

    WEATHER

    Weather around the country
    Home page  >  Article | Previous article | Next article

    QUICKLINKS AND VIEW OPITONS

  • Articles with Recent Comments
  • Recent Forum Topics
  • Summary View
  • Headline View
  • Archive of Quotes
  • Follow @fatnews

    The FDA’s Flawed System of How Antidepressants Get Approved; Negative Trials Ignored


    Posted by .(JavaScript must be enabled to view this email address)
    Sunday, August 14, 2016 10:38 am Email this article

    Irving Kirsch, PhD from Harvard Medical School tells how antidepressants get approved by the FDA and why it is a flawed system.

    Only Two Positive Drugs Studies Needed for Approval, While Negative Trials Ignored

    He notes that drug companies only have to provide two studies showing positive results to get a drug approved regardless of how many trials failed to show any benefit.

    “The FDA requires two adequately conducted clinical trials showing a significant difference between drug and placebo,” Kirsch writes.

    “But there is a loophole: There is no limit to the number of trials that can be conducted in search of these two significant trials.

    “Trials showing negative results simply do not count.

    “Furthermore, the clinical significance of the findings is not considered.

    “All that matters is that the results are statistically significant.”

    Example of Something that Might Be Statistically Significant, but Clinically Meaningless

    Kirsch gives an example of something that might be statistically significant, but not clinically significant, saying that if they studied a large group of people and found that smiling increases life expectancy by 5 minutes, this might be statistically significant, but clinically meaningless.

    Approval of Vilazodone (Viibryd®)

    “The most egregious example of the implementation of this criterion is provided by the FDA’s approval of vilazodone [Viibryd®] in 2011,” Kirsch continues.

    “Seven controlled efficacy trials were conducted.

    “The first five failed to show any significant differences on any measure of depression, and the mean drug-placebo difference in these studies was less than 1/2 point on the [Hamilton Depression Scale], and in two of the three trials, the direction of the difference actually favored the placebo.

    “The company ran two more studies and managed to obtain small but significant drug-placebo differences (1.70 points).

    “The mean drug-placebo difference across the seven studies was 1.01 [Hamilton Depression Scale] points.

    “No mention is made of the five failed trials that preceded the two successful ones.

    “The failure to mention the unsuccessful trials was not merely an oversight; it reflects a carefully decided FDA policy dating back for decades.

    FDA Director Thinks Excluding Info About Negative Drug Trials is Potentially ‘False and Misleading’

    Kirsch continues by saying,

    “To my knowledge, there is only one antidepressant in which the FDA included information on the existence of negative trials.

    “The exception is citalopram [Celexa], and the inclusion of the information followed an objection raised by Paul Leber, who was at the time the director of the FDA Division of Neuropharmacological Drug Products.

    “In an internal memo dated May 4, 1998, Leber wrote:

        “One aspect of the labeling deserves special mention.

        “The [report] not only describes the clinical trials providing evidence of citalopram’s antidepressant effects, but make mention of adequate and well-controlled clinical studies that failed to do so…

        “The Office Director is inclined toward the view that the provision of such information is of no practical value to either the patient or prescriber.

        “I disagree.

        “I believe it is useful for the prescriber, patient, and 3rd-party payer to know, without having to gain access to official FDA review documents, that citalopram’s antidepressants effects were not detected in every controlled clinical trial intended to demonstrate those effects.

        “I am aware that clinical studies often fail to document the efficacy of effective drugs, but I doubt that the public, or even the majority of the medical community, is aware of this fact.

        “I am persuaded that they not only have a right to know but that they should know.

        “Moreover, I believe that labeling that selectively describes positive studies and excludes mention of negative ones can be viewed as potentially ‘‘false and misleading.”

    (Leber, May 4, 1998).

    Irving Kirsh’s book The Emperor’s New Drugs: Exploding the Antidepressant Myth

    Irving Kirsh is the author of the book The Emperor’s New Drugs: Exploding the Antidepressant Myth.

    Robert Whitaker’s book Anatomy of an Epidemic Talked About All of This

    Robert Whitaker’s wonderful book Anatomy of an Epidemic: Magic Bullets, Psychiatric Drugs, and the Astonishing Rise of Mental Illness in America (2010) talks about all of this also.

    Whitaker found that:

    This article was originally published on May 31, 2016.

    Reference

    Kirsch I. Antidepressants and the Placebo Effect. Z Psychol, 2014; 222(3): 128-134.

    The paper is posted here.

    Author’s Contact Info

    Irving Kirsch, PhD
    Beth Israel Deaconess Medical Center Gen. Med. Pricare
    330 Brookline Avenue
    Boston, MA 02215 USA
    Tel. +1 617 945-7827
    Fax +1 617 492-3182
    .(JavaScript must be enabled to view this email address)

     

     

     

    Other Articles About Antidepressants

    Here are links to other articles about antidepressants.

    Antidepressants benefits mostly, if not entirely, due to the placebo effect says Harvard researcher

    If you ask me, no one should take antidepressants, Peter Gotzsche, MD

    Fluoxetine (Prozac), a terrible drug, Peter Gotzsche, MD

    3 False Epidemics: ADHD, Autism and Childhood Bipolar Disorder, Peter Gotzsche, MD

    Risk of suicide caused by SSRI’s grossly underestimated, Peter Gotzsche, MD

    Likely to have been 15 times more suicides on antidepressant than reported by FDA, Peter Gotzsche MD

    ‘Virtually all trials of psychotropic agents are flawed’ says Peter Gotzsche, MD

    Survey found 60% felt emotional numb on antidepressants says Peter Gotzsche, MD

    Antidepressants don’t work for depression, Peter Gotzsche, MD

    DSM-IV created three false epidemics: ADHD, autism and childhood bipolar disorder, Peter Gotzsche MD

    Psychiatry Has Spiraled Out of Control, Peter Gotzsche, MD

    1% of US children up to only four years of age are on psychotropic drugs, Peter Gotzsche, MD

    It Should Be Forbidden To Make a Second Diagnosis While Someone Is On Drugs, Peter Gotzsche, MD

    All Psychiatric Diagnoses and Interventions Can Cause Harm, Peter Gotzsche, MD

    Screening for Depression is Harmful, Peter Gotzsche, MD

    Psychiatric drugs kill more than 500,000 people 65 and older each year, Peter Gotzsche, MD

    Psychiatric drug use could be reduced by 98 percent, Peter Gotzsche, MD

    There is a Huge Epidemic of drug overuse with SSRI’s, Peter Gotzsche, MD

    Psychiatrists Think Psychiatric Drugs Are Effective, Patients Do NOT, Peter Gotzsche, MD

    It Is Doubtful Whether Antidepressants Are Effective For Depression, Peter Gotzsche, MD

    SSRI’s Kill One Of 28 People Above 65 Years Of Age Treated For One Year, Peter Gotzsche, MD

    Many People Suffer Disabling Symptoms For Years Following Antidepressant Withdrawal, Peter Gotzsche

    Prescriptions for antidepressants written in 3 minutes or less, Peter Gotzsche, MD

    Many People Are Wrongly Diagnosed With Schizophrenia, Peter Gotzsche, MD

    One-Fourth of Healthy People [Wrongly] Got A Psychiatric Diagnosis, Peter Gotzsche, MD

    Before and After picture of depressed woman treated with natural approach, Joan Mathews Larson, PhD

    SSRI’s increase risk of suicides, Parkinson’s and restless legs notes Joan Mathews Larson PhD

    SSRI’s may increase risk of breast cancer, notes Joan Mathews Larson PhD

    SSRI’s make things worse notes Joan Mathews Larson, PhD

    Merck hid 3 heart attacks in VIGOR trial of Vioxx, Peter Gotzsche, MD

    Drug studies published in the New England Journal of Medicine are advertisements, Peter Gotzsche, MD

    8 children on the SSRI antidepressant paroxetine (Paxil) had suicidal thoughts, Peter Gotzsche, MD

    Stopping an antidepressant can make people feel depressed or suicidal, Peter Gotzsche, MD

    Psychiatric drugs, drug industry cheated in drug trials, withholding suicides, Peter Gotzsche, MD

    Psychiatry is the drug industry’s paradise, Peter Gotzsche, MD

    Psychiatric drugs can CAUSE psychiatric diseases, Peter Gotzsche, MD

    Psychiatry’s lies, Peter Gotzsche, MD

    Psychiatric drugs has INCREASED the number of people on disability, Peter Gotzsche, MD

    Antidepressants are dangerous, Peter Gotzsche, MD

    Antidepressants increase risk of suicide, Peter Gotzsche, MD

    Psychiatric drugs do ‘more harm than good’ notes Prof. Peter Gotzsche, MD

    Psychiatric drugs create ‘more harm than good’ notes Prof. Peter Gotzsche, MD

    ‘Drug companies don’t sell drugs, they sell lies about drugs’ notes Prof. Peter Gotzsche, MD

    You can get the same benefit without drugs if you are mildly or moderately depressed, Irving Kirsch

    Physical exercise improves mild depression as much as antidepressants notes UK’s Dr. Tim Kendall

    The FDA says unpublished drug trials are unpublished because they were flawed, but Britain disagrees

    Great Britain found that for mild to moderate depression, antidepressants were not effective

    The FDA requires only two studies show positive results to approve a drug

    The serotonin deficiency theory of depression is probably not correct says Walter Brown, MD

    For mild to moderate depression, antidepressants are no better than a placebo, Irving Kirsch, PhD

    17 million Americans taking antidepressants

    Sales of antidepressants total $11.3 billion per year

    Antidepressants and antipsychotic drugs do more harm than good

    Risperdal (risperidone) plus Paxil (paroxetine) causes weight gain of 30-31 lbs in 4-5 months

    Zoloft (sertraline) increases risk of diabetes 25%

    Paxil (paroxetine) increases risk of diabetes 33%

    Elavil (amitriptyline) increases risk of diabetes 43%

    Anafranil (clomipramine) increases risk of diabetes 123%

    Surmontil (trimipramine) increases risk of diabetes 146%

    Antidepressants benefits mostly, if not entirely, due to the placebo effect says Harvard researcher

    180 to 720 mg of rubidium chloride had a significant antidepressant effect in two-thirds of patients

    360-720 mg of rubidium chloride per day for 2 months had rapid antidepressant action in 20 people

    540 mg of rubidium chloride for 3 weeks had antidepressant effect in 15 depressed people

    History of the mineral rubidium as an antidepressant

    If you ask me, no one should take antidepressants, Peter Gotzsche, MD

    Fluoxetine (Prozac), a terrible drug, Peter Gotzsche, MD

    3 False Epidemics: ADHD, Autism and Childhood Bipolar Disorder, Peter Gotzsche, MD

    Risk of suicide caused by SSRI’s grossly underestimated, Peter Gotzsche, MD

    Likely to have been 15 times more suicides on antidepressant than reported by FDA, Peter Gotzsche MD

    ‘Virtually all trials of psychotropic agents are flawed’ says Peter Gotzsche, MD

    Survey found 60% felt emotional numb on antidepressants says Peter Gotzsche, MD

    Antidepressants don’t work for depression, Peter Gotzsche, MD

    DSM-IV created three false epidemics: ADHD, autism and childhood bipolar disorder, Peter Gotzsche MD

    Psychiatry Has Spiraled Out of Control, Peter Gotzsche, MD

    1% of US children up to only four years of age are on psychotropic drugs, Peter Gotzsche, MD

    It Should Be Forbidden To Make a Second Diagnosis While Someone Is On Drugs, Peter Gotzsche, MD

    All Psychiatric Diagnoses and Interventions Can Cause Harm, Peter Gotzsche, MD

    Screening for Depression is Harmful, Peter Gotzsche, MD

    Psychiatric drugs kill more than 500,000 people 65 and older each year, Peter Gotzsche, MD

    Psychiatric drug use could be reduced by 98 percent, Peter Gotzsche, MD

    There is a Huge Epidemic of drug overuse with SSRI’s, Peter Gotzsche, MD

    Psychiatrists Think Psychiatric Drugs Are Effective, Patients Do NOT, Peter Gotzsche, MD

    It Is Doubtful Whether Antidepressants Are Effective For Depression, Peter Gotzsche, MD

    SSRI’s Kill One Of 28 People Above 65 Years Of Age Treated For One Year, Peter Gotzsche, MD

    Many People Suffer Disabling Symptoms For Years Following Antidepressant Withdrawal, Peter Gotzsche

    Prescriptions for antidepressants written in 3 minutes or less, Peter Gotzsche, MD

    Many People Are Wrongly Diagnosed With Schizophrenia, Peter Gotzsche, MD

    One-Fourth of Healthy People [Wrongly] Got A Psychiatric Diagnosis, Peter Gotzsche, MD

    High histamine levels cause compulsion, low levels irritability, Joan Mathews Larson PhD

    180 to 720 mg of rubidium chloride had a significant antidepressant effect in two-thirds of patients

    360-720 mg of rubidium chloride per day for 2 months had rapid antidepressant action in 20 people

    540 mg of rubidium chloride for 3 weeks had antidepressant effect in 15 depressed people

    History of the mineral rubidium as an antidepressant

    Articles on the same subject can be found here:


    COMMENTS

    Please feel free to share your comments about this article.


    Name:

    Email:

    Comments:

    Please enter the word you see in the image below:


    Remember my personal information

    Notify me of follow-up comments?



    © Copyright 2003-2017 - Larry Hobbs - All Rights Reserved.