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The numerous benefits of time-restricted feeding, limiting eating to only 8 hours per day
Friday, November 23, 2012 9:46 am Email this article
The benefits of time-restricted feeding, that is, limiting eating to 8 hours per day (and fasted 16 hours per day), as noted in a recent mouse study which compared time-restricted feeding of 8-hours per day to an ad lib diet where food was available 24-hours per day, include:
- decreased body fat
- improvement in glucose tolerance
- decrease in leptin resistance
- decrease in fatty liver
- decrease in inflammation
- increase in motor coordination
- a higher amplitude of circadian rhythms and metabolic rhythms.
The problems seen in mice that were given access to food 24-hours per day (an ad lib diet) include:
- increased in body fat
- decrease in glucose tolerance
- increase in leptin resistance
- increase in fatty liver
- increase in inflammation
- decrease in motor coordination
- a lower amplitude of circadian rhythms and metabolic rhythms.
High-Fat Diet available 8-hours per day vs 24-hours per day
Groups of mice were given access to a high-fat (61% fat) diet either 8-hours per day or 24-hours per day.
Mice given access to High-Fat Diet 24-hours per day weighed 38% more than mice given access to food 8-hours per day
By the end of the 4.5 month study, the mice given access to a high-fat diet 24-hours per day weighed 38% more than the mice given access to the same high-fat diet only 8-hours per day.
The weight of the mice given access to a high-fat diet 24-hours per day was 47 grams versus 34 grams for the mice given access to the same high-fat diet only 8-hours per day.
Hatori M, Vollmers C, Zarrinpar A, DiTacchio L, Bushong EA, Gill S, Leblanc M, Chaix A, Joens M, Fitzpatrick JA, Ellisman MH, and Panda S. Time-restricted feeding without reducing caloric intake prevents metabolic diseases in mice fed a high-fat diet. Cell Metab, 2012 Jun 6; 15(6): 848-860.
Author’s Contact Info
Salk Institute for Biological Studies
La Jolla, CA 92037, USA
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